gene therapy PhD Projects, Programmes & Scholarships

We have 44 gene therapy PhD Projects, Programmes & Scholarships

Gene therapy for neuromuscular diseases

Royal Holloway, University of London School of Biological Sciences

We are accepting candidatures for PhD students enthusiastic about finding cures for neuromuscular diseases or willing to explore and learn gene therapy technologies using models of neuromuscular diseases. Read more

Supervisor: Dr AB Malerba

Year round applications PhD Research Project Self-Funded PhD Students Only

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Impact of adeono-associated virus (AAV) formulation on utility

Medicines and Healthcare Products Regulatory Agency Vaccines team

AAV gene therapy clinical trials are expanding to address unmet medical needs and the breadth of diseases to which AAVs are applied is increasing rapidly with over 200 trials registered globally. Read more

Supervisor: Dr S Kempster

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Next Generation Oligonucleotide Drugs for Gene Therapy

University of Portsmouth School of Pharmacy and Biomedical Sciences

Synthetic oligonucleotides are short strands of DNA that can be used to treat or manage a wide range of diseases, for example by silencing malfunctioning genes. Read more

Supervisor: Dr D Rusling

Year round applications PhD Research Project Self-Funded PhD Students Only

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Development of new molecular therapies to treat motor neuron disease (MND)

Macquarie University Centre for MND Research

The battle against Motor Neuron Disease (MND) is entering an exciting phase with the development of gene therapies aimed at reducing pathogenic proteins. Read more

Supervisors: Assoc Prof AL Lee, Assoc Prof MM Morsch

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Investigating the effect of promoters on gene expression in novel adeno-associated virus (AAV) producer cell lines.

Medicines and Healthcare Products Regulatory Agency Biotherapeutics and Advanced Therapies Team

We are seeking an enthusiastic candidate to work on an exciting and highly collaborative research project, aimed at identifying and characterising optimal promoter sequences to control expression of AAV genes to engineer novel stable AAV producer cell banks. Read more

Supervisor: Dr C Kerridge

19 April 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Development of novel lipid nanoparticles (LNPs) for targeted gene delivery to cancer cells

University of Portsmouth School of Pharmacy and Biomedical Sciences

Applications are invited for a self-funded, 3 year full-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Roja Hadianamrei and Dr Sassan Hafizi. Read more

Supervisors: Dr R Hadianamrei, Dr S Hafizi

Year round applications PhD Research Project Self-Funded PhD Students Only

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A Patient-derived 3D humanized model of ADCY5-related disease to accelerate therapeutic approaches for patients

Great Ormond Street Hospital for Children NHS Trust BRC Translational Research (Non-Clinical) PhD Studentships

ADCY5-related disease is a genetic disorder caused by mutations in the ADCY5 gene, which encodes for the isoform 5 of adenylyl cyclase (ADCY5)1. Read more

Supervisors: Dr S Barral, Dr M Kurian, Dr HZ Zhou

15 May 2024 PhD Research Project Funded PhD Project (UK Students Only)

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Peptide-based nanoparticles for brain targeted gene delivery.

Queen’s University Belfast School of Pharmacy

Gene therapy has the potential to provide therapeutic benefit to millions of people with neurodegenerative diseases and cancer. Delivery into the brain is hampered by the blood-brain barrier (BBB), which limits the efficacy of both conventional and novel therapies at the target site. Read more

Supervisors: Dr E McErlean, Prof H McCarthy

Year round applications PhD Research Project Self-Funded PhD Students Only

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Therapeutic potential of extracellular vesicles from different mesenchymal stem cell subtypes

University of York York Biomedical Research Institute

Human mesenchymal stem/stromal cells (MSCs) are found in adult tissues such as bone marrow and are able to differentiate into bone, cartilage and fat tissues. Read more

Supervisor: Prof P G Genever

Year round applications PhD Research Project Self-Funded PhD Students Only

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EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

University College London Department of Biochemical Engineering

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more

Funded PhD Programme (UK Students Only) EPSRC Centre for Doctoral Training

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Creation of cell lines modelling complex karyotype in B cell lymphomas using CRISPR/Cas9

University of Liverpool Institute of Systems, Molecular and Integrative Biology

Chronic lymphocytic leukaemia (CLL) and diffuse large B cell lymphoma (DLBCL) make up more than half of all the newly diagnosed cases of non-Hodgkin’s lymphoma (NHL), the 6th most common cancer in the UK. Read more

Supervisors: Dr J Slupsky, Dr N Kalakonda, Dr M Glenn

1 May 2024 PhD Research Project Self-Funded PhD Students Only

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Human Genetics, Genomics and Disease: Integrating fusion-proteins molecular signatures for advancing sarcoma diagnosis and therapy

University of Edinburgh College of Medicine and Veterinary Medicine

Research Group: MRC Human Genetics Unit

Location. MRC Human Genetics Unit, University of Edinburgh, UK & Max Delbrück Center, Berlin, Germany. Supervisors. Dr Nezha Benabdallah, Dr Daria Bunina. Read more

Supervisor: Dr NB Benabdallah

19 May 2024 PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Precision Therapy for NBAS-related disorder

University of Sheffield School of Medicine and Population Health

It is very well recognised that rare diseases offer the potential to uncover new information about mechanisms underlying a range of phenotypes. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Stochastic modelling and inference for live-cell gene expression time-series data to unravel the mechanisms of stem cell differentiation

University of St Andrews School of Mathematics and Statistics

Research Group: Division of Statistics

This project will develop statistical methodology for noisy time-series data and stochastic computational models to analyse live-cell imaging data provided by the lab of our collaborator Dr Cerys Manning at the University of Manchester. Read more

Supervisor: Dr G Minas

Year round applications PhD Research Project Competition Funded PhD Project (Students Worldwide)

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Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

University of Nottingham School of Medicine

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more

Supervisors: Prof K Gaston, Dr S Jayaraman

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 44 gene therapy PhD Projects, Programmes & Scholarships

gene therapy PhD Projects, Programmes & Scholarships

We have 44 gene therapy PhD Projects, Programmes & Scholarships

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