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We have 273 genetic PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships



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genetic PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 273 genetic PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Predicting efficacy and safety of drugs using genetic and population data

A major factor influencing the cost of drugs is the high rate of failure during clinical trials due to inefficacy (failure to have the desired effect) or safety issues (adverse effects). Read more

A genetic atlas of human molecular phenotypes for causal modelling of disease

Genome wide association studies enable the mapping of genetic effects to molecular phenotypes (such as gene expression levels or protein levels in specific tissues), and those genetic effects can then be mapped to disease traits for causal inference using a statistical framework known as Mendelian randomisation (e.g. Read more

How does parental education increase risk to ADHD in the offspring?

Background. Attention Deficit Hyperactivity Disorder (ADHD) is a chronic neurodevelopmental condition, characterised by persistent difficulties in the areas of attention span/impulse control. Read more

Deep phenotyping of genetic syndromes associated with autism

Autism is an extremely heterogeneous condition. Some of this variability results from genetic heterogeneity. Some rare genetic conditions appear to have an increased prevalence of autism. Read more

Reproductive medicine options in families with genetic Motor Neuron Disease

Up to 20% of people with Motor Neuron Disease (MND) have an identifiable monogenic cause. Overwhelmingly, these are autosomal dominant genes with a 50% chance of transmission to offspring, who will in turn have a high chance of developing MND. Read more

Development and Evolution of Shapes: Investigating the genetic pathways governing the leaf shape in Arabidopsis

The shapes and sizes of organisms and organs are scrupulously conserved within a species. What regulates the shapes and sizes of organisms and their lateral organs are intriguing and fundamental questions in Biology. Read more

Genetics: Investigating the functional effect of novel genes and genetic variants in malignant hyperthermia susceptibility using model systems

Malignant hyperthermia (MH) is an inherited condition, where patients exposed to anaesthetic drugs are susceptible to a dramatic hyperthermic and hypermetabolic response that can contribute to a significant proportion of post-operative morbidity and deaths. Read more

Identifying novel regulators of haematopoiesis using flies

Supervisors. Iwan Evans (primary supervisor); Steve Brown (Biosciences, secondary supervisor). Project details. Control of blood cell proliferation, survival and activation is critical to the health of an organism. Read more

Population genetic engineering: Innovative approaches to control vector-borne diseases

Fully funded studentship available for entry in October 2023. This 4-year PhD studentship provides inter-disciplinary training at the intersection of population genetics, evolution, and synthetic biology, with a focus on mathematical modelling, statistics, and computational methods. Read more

Sometimes Correlation does Equal Causation: Developing Statistical Methods to Determine Causality Using Genetic Data

There is a well-known mantra that correlation does not necessarily equal causation. This is why randomized controlled trials in which participants are physically randomized into treatment and placebo groups are the gold standard for assessing causality in epidemiological investigations. Read more

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