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genetic manipulation PhD Projects, Programs & Scholarships

We have 24 genetic manipulation PhD Projects, Programs & Scholarships

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  Genetic risk factors underlying impaired cognitive flexibility and neural plasticity in psychiatric disorders.
  Prof J Mellor, Dr MC Ashby
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisors. Prof Jack Mellor (Bristol), Jeremy Hall (Cardiff), Dr Michael Ashby (Bristol), Prof Lawrence Wilkinson (Cardiff). Cian O’Donnell (Bristol.
  Live-imaging and genetic approaches to explore cross-talk between tissue damage, immune dysfunction and infection within novel animal models of cystic fibrosis
  Dr H Weavers, Prof E Mahenthiralingam, Dr D N Sheppard
Application Deadline: 25 November 2019

Funding Type

PhD Type

Cystic fibrosis (CF) is a genetic disorder driven by mutations in the CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) gene.
  Molecular genetic characterization of Drosophila reproductive behaviours for exploitation in insect population control
  Research Group: BBSRC MIBTP
  Dr M Soller
Applications accepted all year round

Funding Type

PhD Type

Female reproductive behaviours in most insects profoundly change after mating leading to rejection of courting males and induction of egg laying.
  Host-pathogen interactions of the Cryptosporidium parasite
  Dr A Sateriale
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Adam Sateriale’s Group based at the Francis Crick Institute (the Crick). Cryptosporidium, or ‘crypto’, is an intracellular parasite that causes a severe diarrhoeal disease known as cryptosporidiosis.
  Creating “super” regulatory T cells to combat rejection, GVHD and autoimmunity through retroviral gene manipulation
  Dr N Jones, Dr S Lee
Applications accepted all year round

Funding Type

PhD Type

Research interests/description of main research theme. Foxp3+CD25+CD4+ regulatory T cells (Treg) have been shown to be essential for the induction of tolerance to foreign organ transplants in experimental models.
  Genome mining of novel antimicrobial natural products from new bacterial strains
  Dr H Deng, Prof M Jaspars
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance (AMR) is rising to dangerously high levels in all parts of the world. In Europe alone, drug-resistant bacteria are estimated to cause 25,000 deaths annually and cost more than US$1.5 billion every year in healthcare expenses and productivity losses.
  Safe-guarding genome integrity during mammalian cell division
  Dr U Gruneberg
Application Deadline: 10 January 2020

Funding Type

PhD Type

The key goal of cell division is the correct segregation of the genetic material over multiple generations. Failure of this process can result in cell death or trigger tumorigenesis.
  Modulating cell signalling regulates morphogenesis of the developing nervous system
  Dr M E Pownall, Dr H V Isaacs
Application Deadline: 30 June 2020

Funding Type

PhD Type

Growth factors such as FGFs and Wnts are important signalling molecules that regulate development and are also known to cause disease when they go wrong.
  Mechanisms of selective cell vulnerability to protein assembly propagation in neurodegenerative disease
  Dr B Falcon
Application Deadline: 3 December 2019

Funding Type

PhD Type

The assembly of a small number of proteins into amyloid structures within neurons and, in some cases, glia underlies neurodegenerative disease.
  The production of alcohols as commodity chemicals/ biofuels using yeast as a vehicle
  Prof M Ashe, Prof C M Grant, Dr J-M Schwartz, Dr J Winterburn
Applications accepted all year round

Funding Type

PhD Type

Crude oil represents probably the most important natural resource to industrial nations. As well as fuel, crude oil is used to produce a host of chemicals that govern modern day life.
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