We have 11 head and neck PhD Projects, Programmes & Scholarships

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head and neck PhD Projects, Programmes & Scholarships

We have 11 head and neck PhD Projects, Programmes & Scholarships

Investigation of antagonism of multiple RGD-binding integrins as a therapeutic strategy in advanced head and neck cancer

  Research Group: Institute of Cancer Therapeutics
Background. The integrins are a family of transmembrane receptors which mediate cell-cell and cell-ECM adhesion, and signalling across the cell membrane involved in pathways controlling cell migration, proliferation, differentiation, cell survival and apoptosis. Read more

Recreating the Head and Neck Cancer Microenvironment

Project details. Head and Neck cancer (HNC) is a significant cause of mortality and morbidity worldwide, ranking as the 6th most common cause of cancer incidence and mortality in the world. Read more

Neurovascular transmission in carotid arteries (FOUNTAINS_U25BHF)

Primary supervisor - Prof Samuel Fountain. Carotid arteries perfuse the head and neck, supplying the brain and eyes through the internal carotid artery, and extra-cranial tissue through the external carotid artery. Read more

Circadian rhythm effects on radiotherapy for prostate and other cancers

  Research Group: Human & Medical Genetics
Radiotherapy is used to treat more than 50% of cancer patients, but up to a quarter of patients suffer side effects that can affect their quality of life in the long-term. Read more

Understanding how mutations in the kinase TLK2 cause a neurodevelopmental disorder

Tousled-like kinase 2 (TLK2) was recently identified as a novel genetic locus for a neurodevelopmental disorder. Patients predominantly possess de novo mutations in TLK2, leading to a reduction in its expression or kinase activity. Read more

Designing and evaluating novel nanotherapeutics to enhance the effectiveness of radiotherapy in the treatment of solid cancers.

One in two cancer patients will receive radiotherapy as part of their treatment. For patients with a localised cancer diagnosis effective radiotherapy represents the best chance of a curative outcome, however, is not without risk. Read more
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