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We have 751 health information PhD Projects, Programmes & Scholarships

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We have 751 health information PhD Projects, Programmes & Scholarships

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Synthesis of novel metal chelators against Parkinson’s Disease (ref: SF22/HLS/APP/TETARD)

The involvement of iron in the development of Parkinson’s Disease is now well recognised. Iron seems to be accumulating in the neurons of sufferers and is involved in the formation of reactive oxygen species that cause oxidative damage to neurons, resulting in their death. Read more

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Development of Nanomaterials for Targeting the Bacteria–Host Interface in Cystic Fibrosis Airways

The attachment of Pseudomonas aeruginosa (PA) to the airway mucus in the lungs of people with cystic fibrosis (CF) represents an important step in airway colonization and the subsequent development of lung infection. Read more

3D-Printing of implantable devices for the treatment of chronic conditions

Non-adherence to treatment costs the NHS more than £500M each year. Adherence is especially important when treating patients with chronic conditions that require lifetime pharmacological treatment, such as schizophrenia, Parkinson’s disease, HIV and Alzheimer’s disease. Read more

Bacteriotherapy to treat non-alcoholic fatty liver disease (BERAZA_Q23MMBC)

Obesity has reached epidemic proportions in the UK. Over 60% of UK adults are either obese or overweight, and one in three has liver steatosis, an accumulation of fat in the liver considered to be an early stage of non-alcoholic fatty liver disease (NAFLD). Read more

Opioid overdose deaths: Understanding the lethal interactions between benzodiazepines and opioids to develop new harm reduction strategies

The overall aim of this project is to understand how benzodiazepines and opioids interact to increase the likelihood of fatal overdose (both from a neuro-biological and drug-user perspective) so that we can help design new harm reduction interventions that could reduce the number of overdoses in the population. Read more

Fish, predator and collective behaviour

How do animals interact in groups? What benefits and costs can this bring? What are the ecological effects of social living? How do differences between… Read more

An investigation of the influence of life-long metabolic factors that contribute to age-related eye diseases

Primary open-angle glaucoma is a major source of disability and blindness. Genetic studies have been hugely successful in improving our understanding of this disease, but the mechanisms through which, in interaction with non-genetic factors, they can lead to glaucoma is not well understood. Read more

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