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heart PhD Projects, Programmes & Scholarships

We have 401 heart PhD Projects, Programmes & Scholarships

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We have 401 heart PhD Projects, Programmes & Scholarships

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Inter- and intra-cellular signalling in the development of fibrosis in the hypertensive heart

Project Overview. Heart failure is a leading cause of morbidity and mortality worldwide. In terms of volume, the normal heart is composed mostly of terminally-differentiated contractile cells (cardiomyocytes), responsible for the pump action of the heart. Read more

Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue

Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more

Simulating the physiological deformation of the semilunar heart valves using in vitro and in silico techniques

Applications are invited for a self-funded, 3-year full-time or 6-year part time PhD project. The PhD will be based in the School of Mechanical and Design Engineering in conjunction with the National Heart and Lung Institute (NHLI), Harefield Hospital, Imperial College, and will be supervised by. Read more

A spoonful of sugar makes the medicine go...wrong: Disruption of the intrinsic protection in the heart by hyperglycaemia

Hyperglycaemia at the time a patient suffers a heart attack has been shown to cause a poorer outcome for the patient. This can be an increased infarct size, poorer long-term prognosis, increased risk of developing heart failure, but also an increased likelihood of death from the initial cardiac event. Read more

PMCA1 – a potential target for the treatment of heart failure

Our research group is focused on understanding the molecular mechanisms underlying the development and progression of heart failure and in doing so identifying potential new targets for its treatment. Read more

The role of the spliceosome protein Prpf8 in embryonic development

Errors that occur during cardiac development cause congenital heart defects (CHD). Despite the prevalence of CHD, the developmental processes that ensure the heart forms correctly are still being elucidated. Read more

Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials

Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more

Characterising congenital heart disease variants in Drosophila

Congenital heart disease (CHD) is the most common congenital defect affecting approximately 1% of live births contributing to a significance incidence of birth-defect related mortality. Read more

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