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heart PhD Projects, Programmes & Scholarships
We have 419 heart PhD Projects, Programmes & Scholarships
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Examining the mechanisms that cause cardiovascular disease by studying the heart or adipose tissue
Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more
Biomechanical signalling in human heart disease
About the Project. The human heart undergoes more than 2 billion beats throughout an individual's lifetime, with its rhythm precisely regulated by signalling events that continuously adapt to the biomechanical stress exerted on the ventricular walls. Read more
AI Evaluation of Heart Muscle Function
Applications are invited for a fully funded 3,5 year full-time PhD studentship (including home tuition fees, annual stipend and consumables) starting on 1st February 2024. Read more
Toxic effects of breast cancer treatment on the heart: using artificial intelligence to predict the potential for heart failure
Project Overview. . Breast cancer is the most common cancer worldwide with ~15% of cases caused by a single gene, HER2. These women are treated with an antibody therapy (e.g. Read more
Innovative Biological Scaffolds for Regenerative Replacement of Dysfunctional Heart Valves
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2023/24. Read more
Epigenetic regulation in heart failure and cardiac sudden death
A large proportion of heart failure patients die from cardiac sudden death (SCD), a direct result of lethal ventricular arrhythmias, which is the principal cause of mortality from heart disease worldwide and remains a major unresolved public health problem. Read more
Providing insights into the molecular understanding of heart development and the formation of congenital heart defects.
Our research aim is to understand how the heart develops and then how it goes wrong to give rise to congenital heart defects (CHDs). Read more
Definition of endophenotypic features indicative of genetic variants that cause congenital heart disease, through cardiac organoid (cardioid) modelling
Recent advances in cardiac organoid modelling may yield novel approaches to generating “disease in a dish” models that will provide opportunities to dissect variant-specific mechanisms in congenital heart disease (CHD). Read more
PMCA1 – a potential target for the treatment of heart failure
Our research group is focused on understanding the molecular mechanisms underlying the development and progression of heart failure and in doing so identifying potential new targets for its treatment. Read more
The role of the spliceosome protein Prpf8 in embryonic development
Errors that occur during cardiac development cause congenital heart defects (CHD). Despite the prevalence of CHD, the developmental processes that ensure the heart forms correctly are still being elucidated. Read more
Improving risk stratification and diagnosis of heart failure using Cardiac Output Response to Stress Test
The research team led by Professor Jakovljevic developed an easy-to-use, non-invasive, patient friendly Cardiac Output Response to Stress (CORS) test to enhance risk stratification and early diagnosis of heart failure (HF) in primary care. Read more
Identifying the critical downstream targets of sustained ROS production during caudal fin and heart regeneration in zebrafish
A primary goal in regenerative medicine is to identify and implement novel treatments aimed at improving our ability to regenerate injured, diseased or aged tissues and organs, including the heart. Read more
Cellular protein quality control in diabetes-associated heart disease: The insight into mechanisms and therapeutic potentials
Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more
Investigation into inflammatory drivers in congenital heart disease
Background. Birth defects are complex developmental phenotypes affecting ~6% of births worldwide. Congenital heart disease (CHD), accounting for 1/6th of these defects is still not fully understood, with the role of inflammation and the contribution of inflammatory cells in disease progression still to be elucidated. Read more
Cardiac and skeletal muscle progenitor cells - driving regeneration ability by tryptophan metabolites
The School of Biomedical Sciences invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2023/24. Read more