Recent advances in cardiac organoid modelling may yield novel approaches to generating “disease in a dish” models that will provide opportunities to dissect variant-specific mechanisms in congenital heart disease (CHD). Read more
Background. Birth defects are complex developmental phenotypes affecting ~6% of births worldwide. Congenital heart disease (CHD), accounting for 1/6th of these defects is still not fully understood, with the role of inflammation and the contribution of inflammatory cells in disease progression still to be elucidated. Read more
Cardiovascular complications are the leading causes of diabetes mortality. With the exception of vascular and valvular injuries, diabetic cardiomyopathy (DCM) is a distinct myocardial disease, which is characterised by abnormal cellular metabolism and defects in organelles function, leading to impaired cardiac function. Read more
Heart failure has a serious impact on our society and once diagnosed has a poor survival rate. In the United Kingdom, there are about 1.5 million people living with the after-effects of a heart attack. Read more
Full scholarship details are. here. Background. This Scholarship has been established to provide financial assistance to a master's by research or PhD student to undertake research in the cardiovascular rehabilitation and secondary prevention fields as part of a NHMRC Synergy Grant. Read more
Researchers, practitioners, and policy makers have shown that physical, social, and mental health research disparities exist between lesbian, gay, bisexual, transgender, queer, intersex, plus (LGBTQI+) populations, and. Read more
A large proportion of heart failure patients die from cardiac sudden death (SCD), a direct result of lethal ventricular arrhythmias, which is the principal cause of mortality from heart disease worldwide and remains a major unresolved public health problem. Read more
Platelets are small blood cells that play a vital role in the chronic and acute progression of Cardiovascular Disease (CVD), and also have roles in immunity, inflammation, cancer metastasis, Alzheimer's disease and a range of infections, such as dengue, HIV-1, malaria, and COVID-19. Read more
Heart disease is the leading cause of death worldwide accounting for one-third of deaths. Platelets play a central role in acute coronary syndromes (ACS) through the development of arterial thrombosis. Read more
Common heart diseases such as heart failure (HF) and coronary heart disease (CHD) are characterized by cardiomyocyte loss due to necrosis and apoptosis. Read more
Heart attacks occur when a blockage called a thrombosis develops in the blood vessels of the heart which is a major cause of morbidity and mortality. Read more
The idiopathic inflammatory myopathies are a spectrum of rare autoimmune disorders characterized by inflammation of muscle tissue (myositis), which leads to muscle weakness and fatigue, and heterogeneous systemic organ involvement. Read more
Background. Non-alcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease in the UK due to the obesity and type 2 diabetes epidemics. Read more
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