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helminth PhD Projects, Programs & Scholarships

We have 8 helminth PhD Projects, Programs & Scholarships

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We have 8 helminth PhD Projects, Programs & Scholarships

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Helminth products as macrophage “trainers”: a novel therapeutic tool for the treatment of immune mediated diseases

The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more

Self-funded BMS project: Helminth-induced changes to host haematopoiesis - a permanent problem?

More than a quarter of the global population is infected with a parasitic worm that causes a range of diseases. On-going work in our laboratories is focused on understanding how parasites such as schistosomes cause wide-ranging changes to host bone marrow and re-programme mammalian haematopoiesis. Read more

How regulatory immunological cues (re)programme cellular metabolism to control effector T cell behaviour and function

Upon activation a T cell transitions from a state of semi-quiescence to a state of high activity. During the process of activation the T cell therefore needs to up regulate metabolic pathways to acquire the energy and nutrients required to facilitate the behavioural changes associated with its new functional state. Read more
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