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histone PhD Projects, Programs & Scholarships

We have 30 histone PhD Projects, Programs & Scholarships

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  ChromDesign-ITN: Spatio-temporal organization of histone variants: from nucleosomes to nuclei (subproject ESR8); Hosting institution: Institut Curie, Paris, France
  Prof Genevieve Almouzni, Prof S Mundlos
Application Deadline: 21 December 2018
"ChromDesign” is a European innovative and interdisciplinary Research and Training network, which aims to characterize the impact of the 3D chromatin organization on gene regulation during cellular differentiation and in several human disorders, and to train junior researchers in the biomedical field, either in academia or in the private sector.
  Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
  Research Group: BBSRC MIBTP
  Dr M Soller, Prof F Mueller
Applications accepted all year round
Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017).
  Developing Proteolysis Targeted Chimeras (PROTACs) to individual class-I Histone Deacetylase complexes
  Dr S Cowley
Application Deadline: 6 January 2019
The highly related histone deacetylases (HDAC) 1, 2 and 3 regulate global levels of lysine acetylation as the catalytic components of five distinct multi-protein complexes.
  Structure and functional studies of histone deacetylase complexes
  Prof J Schwabe, Dr J Hodgkinson
Application Deadline: 6 January 2019
Histone deacetylase complexes trigger the programmed repression of regions of the genome which is one of the critical first steps in epigenetic regulation.
  Transcriptional Control of Stem Cell Differentiation
  Research Group: Gene Expression
  Dr S Cowley
Applications accepted all year round
The ability to regulate the transcriptional activity of protein coding genes is one of the most fundamental processes of life. The transcriptional potential of a gene is directly related to its chromatin context, which in turn, is influenced by the covalent modification of its core histone components.
  Development of treatment for Osteoarthritis by blocking metalloproteinases
  Prof G Bou-Gharios
Applications accepted all year round
We aim to understand how MMP13 is transcriptionally regulated and whether a newly identified enhancer is involved in normal and osteoarthritic cartilage.
  ChromDesign-ITN: Analysis of MLL family of proteins in leukaemias (subproject ESR2); Hosting institution: Centre for Genomic Regulation - CRG, Barcelona, Spain
  Dr Luciano DiCroce, Prof Genevieve Almouzni
Application Deadline: 21 December 2018
"ChromDesign” is a European innovative and interdisciplinary Research and Training network, which aims to characterize the impact of the 3D chromatin organization on gene regulation during cellular differentiation and in several human disorders, and to train junior researchers in the biomedical field, either in academia or in the private sector.
  H3.3 and its chaperones in the nervous system
  Dr D Bano
Applications accepted all year round
The German Center for Neurodegenerative Diseases (DZNE) investigates the causes of diseases of the nervous system and develops strategies for prevention, treatment and care.
  Role of the SWI/SNF complex in the nervous system
  Dr D Bano
Applications accepted all year round
The German Center for Neurodegenerative Diseases (DZNE) investigates the causes of diseases of the nervous system and develops strategies for prevention, treatment and care.
  Chromatin and maintenance of genome stability
  Dr A Chambers
Applications accepted all year round
Within eukaryotes, DNA is packaged into chromatin. The basic unit of chromatin is the nucleosome, formed by the wrapping of ~147 bp of DNA around an octamer of histones proteins.
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