The European FREIA project. , which both supervisors are part of, is specifically designed to address how female reproductive health can be safeguarded from endocrine disrupting chemicals (EDCs). Read more
We are currently recruiting a candidate to undertake fundamental studies in the design and intrinsic self-assembly of DNA in the presence of metals for next-generation sensors and drug delivery systems. Read more
Project summary. Infrared thermography has demonstrated great potential in disease screening and detection, with applications in vascular disorder diagnostics, breast cancer detection, fever screening and dermatology. Read more
Proteins are extensively regulated by dynamic, often reversible post-translational modifications (PTMs). This process allows cells to respond rapidly to environmental factors, be that e.g. Read more
Healthy ageing starts from conception. Environmental influences during early development affect the risk of developing chronic diseases in later life and impact a healthy ageing trajectory. Read more
Despite representing only ~20% of the entire neuronal population in the neocortex, the GABAergic (Gamma-Aminobutyric Acid) inhibitory interneurons play a pivotal role in most cortical functions. Read more
Research Group:
The Patrick G Johnston Centre for Cancer Research
Start date. 1 September 2022. Large scale functional genomics screens using genome-wide CRISPR screens have enabled the identification of cancer-specific vulnerabilities or “synthetic lethalities” (SLs) at an unprecedented scale. Read more
Autonomous maritime navigation is set to transform the maritime industry providing consistent, continuous and cost-effective navigation free from human error. Read more
Within the sphere of cancer chemotherapy, many commercialised drugs have been obtained by the synthesis of new compounds, from natural sources or by structural modification of natural products. Read more
Background. We recently identified a novel human syndrome caused by mutations in a gene called KMT2C1. Patients with this condition predominantly have developmental delay and intellectual disability indicating the important function of this gene in brain’s normal development and function. Read more
Infection with human papillomavirus (HPV) is associated with ~5% of all human cancers, in particular cervical cancer. Whilst less common, HPV is also associated with the vast majority (~93%) of anal cancers in the UK. Read more
ELAV/Hu proteins comprise a family of highly conserved neuronal RNA binding proteins important for the development of the nervous system and for neuronal functions. Read more
Project aims. The overarching aim is to develop new tools for improved monitoring and prediction of toxigenic fungal and mycotoxin contamination of cereals produced on the Island of Ireland. Read more
At least 40 human disorders, including Huntington disease and myotonic dystrophy, are caused by the expansion of a simple sequence repeat [1]. Read more
In the developing world, parasitic helminths infect a large proportion of the population – up to 1 billion people are infected with soil-transmitted helminth (STH) infections worldwide. Read more
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