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human trafficking PhD Projects, Programmes & Scholarships
We have 13 human trafficking PhD Projects, Programmes & Scholarships
We have 13 human trafficking PhD Projects, Programmes & Scholarships
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Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease
Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway. Read more
Graduate Teaching Assistant PhDs in Law and Criminology
Law and Criminology Graduate Teaching Assistant PhD Scholarships. College of Social Sciences and Arts. Duration. 3.5 years. Bursary £16,062 per annum stipend + full Home tuition fees. Read more
A functional proteomic approach to reveal how receptor tyrosine kinases trafficking specifies cancer cell responses
Background and goals. Cells respond appropriately to their surroundings by activating plasma membrane spanning receptors like Receptor Tyrosine Kinases (RTKs) and thereby adapting long-term outputs (e.g. Read more
Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins
Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more
Regulation of nuclear actin in human cancer
Actin is a cytoskeletal protein that plays essential roles in many cellular processes, such as adhesion, intracellular trafficking, membrane dynamics and motility. Read more
Understanding mechanisms of Notch regulation and misregulation in endocytic pathway
Notch is a developmental signalling receptor with widespread and important roles in metazoan development and also in adult stem cell regulation. Read more
Characterising blood-brain barrier formation and function using zebrafish to understand human vascular hyperpermeability
The blood-brain barrier (BBB) is a highly selectively permeable network of blood vessels within the brain. This barrier is essential for central nervous system (CNS) homeostasis by controlling molecular flux between the blood and the brain and protecting it from pathogens and toxins. Read more
Structure and function of Batten disease proteins
The neuronal ceroid lipofucscinoses are a group of inherited neurodegenerative disorders with primarily childhood onset. The most common form, also known as Batten disease or CLN3 disease, is caused by recessively inherited mutation in the CLN3 gene. Read more
Institute of Molecular, Cell and Systems Biology
Our institute houses a multi-disciplinary centre of excellence conducting fundamental and translational life science research underpinning health and food security. Read more
Cancer cells ‘feed’ on extracellular matrix components under starvation conditions: how can they do it?
Background. The tumour microenvironment (TME) has a key role in promoting tumour formation and progression. In breast and pancreatic cancers, this accompanied by the accumulation of extracellular matrix (ECM) in the TME. Read more
Molecular Mechanisms of Receptor and Ion Channel Regulation in Pain and Inflammation
"Receptors and ion channels are responsible for the transmission of signals across cellular membranes that regulate a plethora of biological and cellular functions. Read more
The functions of the Class II Pi3-kinase signals in vivo
Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies. Read more
Characterising Receptor and Ion Channels Signaling in 3D cultures
The molecular mechanisms that regulate receptors and receptor are complex and are often studied in two-dimensional cell culture systems. Read more
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