G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Background. Despite major advances in cardiovascular health, hypertension remains the risk factor contributing most to the overall burden of disease globally. Read more
This is a unique opportunity to work with the world’s largest research cohort of its kind harnessing detailed 24-hour blood pressure records and cardiovascular and falls outcomes on follow up for more than 26,000 people across three UK City regions. Read more
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Project outline. The incidence of cardiovascular disease amongst women of child-bearing age is increasing. Read more
Intracerebral haemorrhage (ICH) is a catastrophic form of stroke caused by spontaneous bleeding in the brain and is a leading global cause of adult disability. Read more
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Project outline. Immune responses play key roles in cardiovascular diseases (CVD) such as atherosclerosis and hypertension. Read more
'TO APPLY, PLEASE CLICK INSTITUTION WEBSITE'. Project background. The management of chronic diseases, including diabetes, accounts for 50% of clinical biochemistry testing. Read more
Summary. A physically active pregnancy including regular exercise reduces pregnancy complications in women with pre-existing type 2 diabetes (T2D) and supports the health of mother and baby, but most women do not do enough exercise to get this benefit. Read more
A major factor in morbidity and mortality worldwide is end stage renal disease (ESRD). At least 10% of ESRD is caused by focal and segmental glomerulosclerosis (FSGS), a form of steroid resistant nephrotic syndrome. Read more
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