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immunology PhD Projects, Programmes & Scholarships
We have 112 immunology PhD Projects, Programmes & Scholarships
RNA Splicing in Immune Cells: Mechanisms, Regulation, and Predictive Modelling (NDORMS-2025/3)
This DPhil project aims to elucidate the mechanisms of RNA splicing within immune cells, focusing on the computational analysis of alternative splicing events and their impact on immune homeostasis and inflammatory responses. Read more
Engineering Resolution – mRNA targeting of chronic inflammatory disease
mRNA based technologies have revolutionised vaccines and have the potential to modulate not just immunity to pathogens but also re-engineer immune responses to resolve chronic inflammatory disease. Read more
Investigating cross-tissue and cross-disease immune mechanisms using single-cell/spatial multiomics & machine learning/AI-powered language learning tools
Immune cells play a fundamental role in health and disease. We are applying the latest molecular and cellular multi-omics analysis platforms (single-cell and spatial omics) and computational methods to deliver insights into immune cell biology across a range of human tissues (e.g. Read more
Relationship between Tumour microenvironment and atherosclerotic cardiovascular disease during immunotherapy
Tumours actively escape the immune system by inducing an immunosuppressive state where intra-tumoural CD8 T-cells are “exhausted”, expressing an array of checkpoint inhibitory receptors, which results in a lack of effector functions. Read more
Spatial single cell dynamics of immune cells in tumours and lymph nodes
Protective immune responses occur in complex tissue ecosystems, we have developed a range of new technologies including Kaede fluorescent protein cellular tracking system, colorectal cancer models and human tissue slice culture systems. Despite advances in immunoncology, driven by check-point inhibitors, many solid tumours remain refractory to curative therapies. Read more
Determining how immune responses are regulated in the lung and gut by the local environment
The immune system must respond quickly to infection but must also be tightly regulated so it ignores harmless substances and our own tissues. Read more
(BRC) Investigating neutrophil activation and altered epithelial structure in chronic obstructive pulmonary disease
The National Institute of Health and Care Research (NIHR) funds Biomedical Research Centres (BRCs) as experimental medicine centres of excellence via competitive application every five years. Read more
(MRC DTP) Exploring macrophage function in oral health and inflammation
Immune control at mucosal barrier sites requires a delicate balance of effective immunity and repair, processes that are potentially counter-regulatory. Read more
(MRC DTP) Death during fungal infection: to die or not to die, that is the question.
Respiratory infections caused by fungi, bacteria, and viruses rank fourth in the global causes of death according to the World Health Organisation. Read more
(MRC DTP) Investigating Resistin mediated immune suppression in Myeloid Leukaemias
Cancer cells employ a variety of mechanisms to evade detection by the body’s immune system, enabling their own growth and survival. Read more
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Novel mechanisms to reduce steroid burden for patients with asthma
The National Institute of Health and Care Research (NIHR) funds Biomedical Research Centres (BRCs) as experimental medicine centres of excellence via competitive application every five years. Read more
Neuroimmune regulation of rheumatoid arthritis
Rheumatoid arthritis (RA) is an immune mediated inflammatory disease which constitutes a major global healthcare challenge as it causes significant disability and pain. Read more
Vaccine LEGACY – Applying a systems based approach to accelerate vaccine development
New technologies are transforming and accelerating both vaccine development but also the molecular and cellular mechanism regulating the efficacy of human… Read more
Shaping intestinal inflammation by neutrophils: the host-diet-microbiome triad
The global incidence of ulcerative colitis (UC), a predominant form of inflammatory bowel disease, is on the rise worldwide. Neutrophils, as the most abundant circulating immune cell population, are recruited in high numbers to the colon in UC, and are associated with sites of deep ulceration (1). Read more
The role of immunity in cardiovascular disease
The immune system is integral to the cardiovascular health and disease. Targeting inflammation ameliorates cardiovascular outcomes. Read more