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immunotherapy PhD Projects, Programs & Scholarships

We have 33 immunotherapy PhD Projects, Programs & Scholarships

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We have 33 immunotherapy PhD Projects, Programs & Scholarships

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Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

In vitro immunotherapy testing: towards next level personalised treatment identification

  Research Group: Translational Tumour Biology
Around 200 children are diagnosed with high-risk cancer in Australia each year. Over 140 of these children still die due to the occurrence of resistance to traditional chemotherapy. Read more

Expanded potential stem cells for regenerative medicine, immunotherapy, and biotechnology

Embryonic stem cells (ES cells) and induced pluripotent stem cells (iPS cells) are pluripotent and thus hold great promise in regenerative medicine, studying disease mechanisms and drug discovery. Read more

Generating killer cells for immunotherapy against cancer and pathogens

Summary. Natural killer cells (NK) and CD8+ T cells protect us against intracellular pathogens and cancers. This project aims to determine pathways that can drive the growth of particular types of NK and T cells that are optimised to provide better protection from disease. Read more

Exploiting ERK5-signalling to modify T-cell behaviour during tumour progression and radiotherapy response: a new immunotherapy approach?

T-cells can attack tumours (so called anti-tumour responses), causing a reduction in tumour size or even elimination of the tumour. However, in many tumours the tumour “switches off” anti-tumour T-cell responses. Several immunotherapy drugs have been developed that switch anti-tumour T-cell responses back on in patients. Read more

Cancer: Developing 3D multicellular tumour spheroid models to assess EPA-oncolytic viruses combination therapies in vitro

Cancer immunotherapy holds significant promise for the treatment of a range of cancers. Immunotherapy efficacy, such therapeutic antibodies and oncolytic viruses (OVs), have been clinically assessed against a range of solid tumours. Read more

Self-funded BMS project: Resurrecting ancestral human sugars: a novel approach to cancer immunotherapy

Human cell surfaces are coated in a thick layer of sticky sugars [Glycocalyx]. Uniquely, cancer cells are covered with an excess of a sialic acid sugar (Neu5Ac), acting as ‘camouflage’ to avoid the immune system. Read more

Immunotherapy: Manipulating T cell metabolism to improve anti-tumour immunity

The induction of immune responses to tumours can provide long-lasting protection from cancer. In this regard, T cells can suppress tumour growth by directly killing cancer cells and by producing inflammatory cytokines. Read more

MSc by Research programme - Immunotherapy against trypanosomiasis: Proof of concept

Drug discovery for parasitic diseases remains a major challenge and global health need. Significant advances in screening technology and methods to understand the mode of action in the past decade have contributed hugely to our arsenal of biological tools to control these pathogens. Read more

Immune Profiling and Immunotherapy for High-Risk Paediatric Sarcomas

  Research Group: Translational Tumour Biology
Sarcomas are a diverse group of connective tissue tumours that account for ~10% of childhood cancers. However, they are relatively understudied and poorly understood. Read more

Deep immuno-profiling of Aspergillus bronchitis and allergic bronchopulmonary aspergillosis in cystic fibrosis

Applications are invited for a fully-funded 3-year PhD studentship. This studentship is integral to a major Cystic Fibrosis Trust Strategic Research Centre in Fungal Immunotherapy (TrIFIC) made to Imperial College London collaborating with University of Manchester and University of Exeter. Read more

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