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in vitro PhD Projects, Programs & Scholarships

We have 239 in vitro PhD Projects, Programs & Scholarships

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  In vitro assessment of drug sequestration into lysosomes and in silico prediction of implications for drug disposition and therapeutic efficacy
  Dr A Galetin, Dr D Hallifax
Applications accepted all year round

Funding Type

PhD Type

Intracellular concentration of a drug is an important determinant of its efficacy, toxicity, and potential drug-drug interactions [1].
  A 3D in vitro model of wound healing incorporating skin, nerves and immune cells
  Dr A M Rajnicek, Dr H M Wilson
Applications accepted all year round

Funding Type

PhD Type

Diabetes, paralysis, being bed ridden and other conditions can result in chronic wounds that fail to heal, with significant personal consequences for patients and an annual cost of £4.5-5.1 billion annually (Guest et al., 2015) to the National Health Service.
  A multi-tissue in vitro model of osteoarthritis
  Prof M.P. Lewis, Dr D Player
Applications accepted all year round

Funding Type

PhD Type

Osteoarthritis (OA) is a joint disorder which is predominantly found in elderly individuals (Lee et al., 2013), but has recently been linked to sports participation at high levels (Vannini et al., 2016).
  (MRC DTP) Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Application Deadline: 15 November 2019

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  Building the human endometrium in vitro: The role of macrophages in receptive and decidual endometrium to optimise reproductive health
  Dr E Mann, Dr Peter Ruane, Prof J Aplin, Dr L Mohiyiddeen
Applications accepted all year round

Funding Type

PhD Type

The human endometrium is a highly dynamic tissue that rapidly generates over ~20 days and differentiates to form a uterus lining receptive to embryo implantation, further transforming into decidua to support embryonic development, or breaking down before regenerating a few days later.
  In vitro, in vivo and ex vivo investigations of the anti-inflammatory properties of culinary herbs when combined with non-herb foods
  Dr E Opara, Dr M Stolinski, Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Culinary herbs are foods rich in polyphenols and a significant body of work has reported on their (the foods) many properties as a consequence of these compounds.
  Characterisation of in vitro models of human salivary glands and their use in functional studies
  Dr L Bingle, Prof C Bingle
Applications accepted all year round

Funding Type

PhD Type

Saliva is produced by three pairs of major salivary glands and multiple minor glands in the lips, associated with the tongue and also with the palate.
  Identifying inhibitors specific to the OPG-kinome: towards novel treatments for Pulmonary Arterial Hypertension (PAH).
  Prof A Lawrie, Dr R Thompson
Applications accepted all year round

Funding Type

PhD Type

Background. Pulmonary arterial hypertension (PAH) is a fatal progressive disease. Median life expectancy in untreated PAH patients is 2.8 years.
  Controlling the emergent dynamical phenomena in neural circuits engineered in vitro
  Dr N Janson, Dr A Balanov, Dr P Roach
Application Deadline: 1 July 2020

Funding Type

PhD Type

This project will be dedicated to mathematical modelling of the collective dynamics in complex living neural networks engineered in vitro.
  (MRC DTP) Modelling inherited developmental ocular disorders using in vitro organoids to understand retinal stem cell fate decisions
  Dr Cerys Manning, Prof G Black
Application Deadline: 15 November 2019

Funding Type

PhD Type

Inherited developmental disorders account for much of childhood visual impairment. During early eye development stem cells must balance fate decisions between proliferation and differentiation at the same time as undergoing cell migration and morphogenesis to prevent such disorders.
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