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in vitro PhD Projects, Programs & Scholarships

We have 224 in vitro PhD Projects, Programs & Scholarships

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  Prediction of drug release and absorption from oily depots and organogels
  Dr M Marlow, Dr P Gershkovich
Applications accepted all year round
For the last several decades parenteral long-acting oily depots for intramuscular injection (IM) and subcutaneous injection (SC), have been used in the treatment of schizophrenia and in hormone replacement therapy (e.g Fluphenazine decanoate in sesame oil , Prolixin Decanoate® (Bristol-Myers Squibb).
  In vitro assessment of drug sequestration into lysosomes and in silico prediction of implications for drug disposition and therapeutic efficacy
  Dr A Galetin, Dr D Hallifax
Applications accepted all year round
Intracellular concentration of a drug is an important determinant of its efficacy, toxicity, and potential drug-drug interactions [1].
  A 3D in vitro model of wound healing incorporating skin, nerves and immune cells
  Dr A M Rajnicek, Dr H M Wilson
Application Deadline: 29 March 2019
Diabetes, paralysis, being bed ridden and other conditions can result in chronic wounds that fail to heal, with significant personal consequences for patients and an annual cost of £4.5-5.1 billion annually (Guest et al., 2015) to the National Health Service.
  Designing Bioreactors for In Vitro Red Blood Cell Manufacture
  Dr S Moise, Dr M J Ellis
Application Deadline: 31 March 2019
With an increasing global demand for blood units for transfusion, there is much interest in manufacturing red blood cells in vitro.
  Functional coronary artery disease genetics: investigating the role of the candidate gene in models of In vivo cardiovascular disease
  Dr G Douglas, Prof K Channon
Application Deadline: 26 July 2019
Despite significant advancements in its treatment coronary artery disease is the leading cause of death in both the UK and world wide, accounting for over 66,000 deaths in the UK each year.
  Advanced in vitro and in silico models to predict and prevent deep venous thrombosis
  Dr D Vigolo, Dr A Alexiadis
Applications accepted all year round
Deep vein thrombosis (DVT) is a life-threatening and debilitating condition where blood clots form within the deep veins (e.g. the femoral vein in the leg).
  A multi-tissue in vitro model of osteoarthritis
  Prof M.P. Lewis, Dr D Player
Applications accepted all year round
Osteoarthritis (OA) is a joint disorder which is predominantly found in elderly individuals (Lee et al., 2013), but has recently been linked to sports participation at high levels (Vannini et al., 2016).
  Efficacy testing of biomaterial delivered iPS cells in in vitro cultures systems to mimic the degenerate niche
  Prof C Le Maitre, Prof C Sammon
Application Deadline: 31 May 2019
Low back pain (LBP) is a leading cause of disability and morbidity worldwide. It is widely accepted that a major contributor to LBP is intervertebral disc degeneration (IDD).
  In vitro, in vivo and ex vivo investigations of the anti-inflammatory properties of culinary herbs when combined with non-herb foods
  Dr E Opara, Dr M Stolinski, Dr A Chioni
Applications accepted all year round
Culinary herbs are foods rich in polyphenols and a significant body of work has reported on their (the foods) many properties as a consequence of these compounds.
  Development of electrospun fibre membranes to support pluripotent stem cell differentiation and delivery of trabecular meshwork cells
  Dr L Bosworth, Dr C Sheridan
Application Deadline: 30 April 2019
Glaucoma, the "silent thief of sight", is a leading cause of sight loss both globally and in the UK, where a near 330,000 people will be diagnosed by 2020.
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