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in vivo PhD Projects, Programs & Scholarships

We have 277 in vivo PhD Projects, Programs & Scholarships

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  Molecular Mechanisms for the Regulation of IL-10 Production in T Cells
  Dr A O’Garra.
Application Deadline: 12 November 2019

Funding Type

PhD Type

This 4-year PhD studentship is offered in Dr Anne O’Garra’s Group based at the Francis Crick Institute (the Crick). Interleukin (IL)-10 is critical for limiting the immune response to pathogens, therefore preventing immunopathology [1].
  Investigating the remodelling of inhibitory brain circuits in early Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Prof A Randall
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Professor Andrew Randall, Medical School, College of Medicine and Health, University of Exeter. Dr Jonathan Witton, College of Medicine and Health, University of Exeter.
  The influence of Apolipoprotein E genotypes on pathways of neurotransmission measured in vivo. Implications for dementia research
  Dr M De Marco, Prof A Venneri
Applications accepted all year round

Funding Type

PhD Type

Monoaminergic midbrain nuclei are currently emerging as major players in the definition of the pathological changes of early Alzheimer’s disease (AD) stages.
  Targeting ERK5 to enhance the DNA damage response to radiotherapy and chemotherapy
  Dr K Finegan, Dr C Demonacos
Applications accepted all year round

Funding Type

PhD Type

ERK5 is a signalling protein that enables cells to transduce extracellular signals into responses. It is expressed in all tissues and is up-regulated in tumours.
  Developing optogenetic therapies for retinal degeneration
  Prof R Lucas, Dr Nina Milosavljevic
Applications accepted all year round

Funding Type

PhD Type

Retinal degeneration is the leading cause of blindness in developed countries. The new exciting biological approach of optogenetic therapy in which ectopic expression of photosensitive proteins (photopigments) is used to restore photosensitivity, offers a potential breakthrough for treating these conditions.
  In vitro, in vivo and ex vivo investigations of the anti-inflammatory properties of culinary herbs when combined with non-herb foods
  Dr E Opara, Dr M Stolinski, Dr A Chioni
Applications accepted all year round

Funding Type

PhD Type

Culinary herbs are foods rich in polyphenols and a significant body of work has reported on their (the foods) many properties as a consequence of these compounds.
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  The neural circuit basis of spatial memory loss in Alzheimer’s disease. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr J Witton
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Jonathan Witton, College of Medicine and Health, University of Exeter. Dr Michael Ashby, Faculty of Life Sciences, University of Bristol.
  The functions of the Class II Pi3-kinase signals in vivo
  Dr L MacDougall, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies.
  Homeostatic balancing of neuronal excitation and inhibition in vivo
  Dr A Lin
Applications accepted all year round

Funding Type

PhD Type

Neuronal excitation and inhibition are very carefully balanced in the brain, and perturbed excitation/inhibition (E/I) balance has been linked to diseases such as epilepsy, autism and schizophrenia.
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