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in vivo PhD Projects, Programs & Scholarships

We have 249 in vivo PhD Projects, Programs & Scholarships

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  Airway, Liver and Muscle Gene Transfer to Create Therapeutic Protein Factories: utilising experience of in vivo gene transfer and/or in vivo gene editing to understand and manipulate the factors required for effective expression and secretion of therapeutic proteins
University of Oxford Radcliffe Department of Medicine
  Dr S Hyde, Dr D Gill
Application Deadline: 26 July 2019
We are focusing on strategies to deliver therapeutics via in vivo delivery of gene transfer vectors to generate ectopic “protein factories” capable of secreting therapeutic proteins into both the lung lumen and the systemic circulation.
Details
Type/Funding
  Functional coronary artery disease genetics: investigating the role of the candidate gene in models of In vivo cardiovascular disease
University of Oxford Radcliffe Department of Medicine
  Dr G Douglas, Prof K Channon
Application Deadline: 26 July 2019
Despite significant advancements in its treatment coronary artery disease is the leading cause of death in both the UK and world wide, accounting for over 66,000 deaths in the UK each year.
Details
Type/Funding
  Advancing Cellular Imaging in vivo in situ in Humans
University of Dundee School of Science and Engineering
  Dr N Krstajic, Prof G Nabi
Application Deadline: 4 April 2019
Microscopy was invented more than 400 years ago and despite this we are still “stuck” in imaging ex vivo cultures isolated in Petri dish or slide.
Details
Type/Funding
  Regulation of the In Vivo Response to Cardiac Hypoxia – The Role of FIH1
University of Nottingham School of Life Sciences
  Dr M Cole
Applications accepted all year round
Hypoxia-inducible factors (HIFs) are transcription factors present in all mammalian cells, and play a pivotal role in the molecular response to changes in oxygen availability.
Details
Type/Funding
  MRC Precision Medicine DTP: Stromal transcriptomic signatures in prostate cancer metastasis and hormone therapy resistance
University of Edinburgh College of Medicine and Veterinary Medicine
  Research Group: MRC Centre for Reproductive Health
  Dr B Qian, Prof H Y Leung, Dr A Sims, Prof P Wiklund
Application Deadline: 8 April 2019
Background. A tremendous amount of cancer ‘-omics’ data have been generated with the intention to stratify patients for personalized diagnosis and treatment.
Details
Type/Funding
  Molecular mechanisms for the regulation of IL-10 production in T cells
The Francis Crick Institute PhD Programme
  Dr A O’Garra.
Application Deadline: 18 March 2019
This 4-year PhD studentship is offered in Dr Anne O’Garra’s Group based at the Francis Crick Institute (the Crick). Interleukin (IL)-10 is critical for limiting the immune response to pathogens, therefore preventing immunopathology [1].
Details
Type/Funding
  In vitro, in vivo and ex vivo investigations of the anti-inflammatory properties of culinary herbs when combined with non-herb foods
Kingston University Faculty of Science, Engineering and Computing
  Dr E Opara, Dr M Stolinski, Dr A Chioni
Applications accepted all year round
Culinary herbs are foods rich in polyphenols and a significant body of work has reported on their (the foods) many properties as a consequence of these compounds.
Details
Type/Funding
  Homeostatic balancing of neuronal excitation and inhibition in vivo
University of Sheffield Department of Biomedical Science
  Dr A Lin
Applications accepted all year round
Neuronal excitation and inhibition are very carefully balanced in the brain, and perturbed excitation/inhibition (E/I) balance has been linked to diseases such as epilepsy, autism and schizophrenia.
Details
Type/Funding
  Characterizing the in vivo functions of P-Rex1 in breast development and tumourigenesis
University of Manchester Faculty of Biology, Medicine and Health
  Dr A Ucar, Prof K R Brennan, Dr A Malliri
Applications accepted all year round
Breast cancer is the most common cancer in the UK with a lifetime risk of 1-in-8 for women and accounts for 12,000 deaths annually.
Details
Type/Funding
  Academic Endocrine Unit: investigating the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
University of Oxford Radcliffe Department of Medicine
  Prof R Thakker, Dr K Lines, Dr M Stevenson, Dr K Kooblall
Application Deadline: 26 July 2019
Other Potential Supervisors. Dr Asha Bayliss. The Academic Endocrine Unit investigates the molecular basis of endocrine and metabolic disorders that principally affect calcium and phosphate homeostasis.
Details
Type/Funding
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