in vivo PhD Projects, Programmes & Scholarships

We have 223 in vivo PhD Projects, Programmes & Scholarships

Sensitizing AML cells to RAR and VDR ligands (vitamin A and D derivatives) to prevent leukaemia relapse

Medical University of Vienna Institute for Pathophysiologie and Allergy

The doctoral candidate (DC) will perform basic research on leukaemia cell biology in vitro and in vivo at the Department of Clinical Biochemistry and Pharmacology, Faculty of Health Sciences, Ben-Gurion University of the Negev, Israel. Read more

Supervisor: Dr MD Danilenko

29 April 2024 PhD Research Project Funded PhD Project (Students Worldwide)

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Investigating the mechanisms for cardiac fibrosis development and reversal

University of Birmingham Institute of Cardiovascular Sciences

Research interests/description of main research theme. Fibrosis is a hard to treat condition of major socioeconomic importance, with ~45% of all deaths in the developed world being attributed to some type of chronic fibro-proliferative disease and is exemplified by heart disease. Read more

Supervisors: Dr D Pavlovic, Dr C O'Shea

Year round applications PhD Research Project Self-Funded PhD Students Only

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Investigating the impact of inflammation on cardiovascular disease

University of Birmingham Institute of Cardiovascular Sciences

We are seeking talented, motivated students with a passion for research in cardiovascular inflammation and immune-mediated chronic inflammatory diseases to join the group of Dr Asif Iqbal (Dr Asif Iqbal - Institute of Cardiovascular Sciences - University of Birmingham). Read more

Supervisor: Dr A Iqbal

Year round applications PhD Research Project Self-Funded PhD Students Only

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Molecular mechanisms underlying the anti-atherogenic actions of natural products

Cardiff University Cardiff School of Biosciences

Atherosclerosis, the underlying cause of myocardial infarction, stroke and peripheral vascular disease, is responsible for most deaths in the western world with mortality increasing at a marked rate in developing. Read more

Supervisors: Dr D Ramji, Dr T Hughes

Year round applications PhD Research Project Self-Funded PhD Students Only

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Feeding microbes to protect the brain: does the gut microbiota mediate the risk-reducing effects of a healthy diet on Alzheimer’s disease?

Queen Mary University of London Institute of Dentistry

Background. Ways of reducing the risk of developing Alzheimer’s disease (AD) and other dementias are critically needed, given the almost total lack of truly effective therapeutic options, even despite newer anti-amyloid drugs1. Read more

Supervisors: Dr S McArthur, Dr E Hagi-Pavli

Year round applications PhD Research Project Self-Funded PhD Students Only

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Using microRNA inhibitors to boost GABAergic inhibition as a genetic therapy for epilepsy

The University of Manchester Faculty of Biology, Medicine and Health

Epilepsy is a chronic neurological disease characterised by recurrent spontaneous seizures and cognitive co-morbidities. Current small molecule approaches to treating epilepsy are ineffective in a significant portion of cases, and are associated with substantial adverse effects. Read more

Supervisors: Dr G. Morris, Dr R Wykes, Prof R Baines

Year round applications PhD Research Project Self-Funded PhD Students Only

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Activity driven mechanisms of cerebral cortex development in the pathogenesis of intellectual disabilities and schizophrenia

Cardiff University Cardiff School of Medicine

Hodge Centre for Translational Neuroscience. “Towards innovative treatments for mental illness”. Cardiff University Neuroscience and Mental Health Innovation Institute. Read more

Supervisor: Dr FB Bedogni

7 May 2024 PhD Research Project Competition Funded PhD Project (UK Students Only)

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PI3K-Akt expression in dysplastic oral lesions and implications for recurrence and malignant transformation

University of Dundee Dental School

There are around 12,400 new head and neck cancer cases in the UK every year, that's 34 every day (2016-2018) with 4,143 deaths each year. Read more

Supervisors: Prof M Macluskey, Dr I Ellis, Dr M Islam, Dr S. J. Jones

30 June 2024 PhD Research Project Self-Funded PhD Students Only

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Disease mechanisms in the heart

University of Birmingham Institute of Cardiovascular Sciences

We are seeking talented, motivated students with a passion for research in inherited cardiac conditions (cardiomyopathies) and biomechanical stress signalling led by Dr Katja Gehmlich (https://www.birmingham.ac.uk/staff/profiles/cardiovascular-sciences/gehmlich-katja.aspx). Read more

Supervisor: Dr K Gehmlich

Year round applications PhD Research Project Self-Funded PhD Students Only

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Clinical Gastroenterology: Investigation of Fidaxomicin Resistance Mechanisms in Clostridium difficile

University of Leeds Faculty of Medicine and Health

Clostridium difficile is a leading pathogen in healthcare-associated diarrheal infections. C. difficile has a plastic genome with multiple mobile genetic elements and recognized capacity to acquire genes involved in resistance and virulence. Read more

Supervisors: Prof M Wilcox, Prof A O'Neill, Dr J Freeman, Dr I Moura

Year round applications PhD Research Project Self-Funded PhD Students Only

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Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

University of Leeds Faculty of Biological Sciences

Research Group: Astbury Centre for Structural Molecular Biology

Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Supervisors: Prof A O'Neill, Dr M McPhillie, Prof C Fishwick

Year round applications PhD Research Project Self-Funded PhD Students Only

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Unravelling the role of P4HB in skeletal development: towards treatment of heritable bone fragility

University of Sheffield School of Medicine and Population Health

Osteogenesis Imperfecta (OI) affects 1 in 15-20,000 live births and results in a childhood with frequent fractures, reduced mobility and joint problems. Read more

Supervisor: Dr M Balasubramanian

Year round applications PhD Research Project Self-Funded PhD Students Only

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Endothelial glycocalyx damage as a therapeutic target in sepsis-associated Acute Kidney Injury

University of Bristol Bristol Medical School

Sepsis is the leading cause of acute kidney injury (sAKI), associated with high morbidity and mortality.1,2 Unfortunately, there is no treatment for sAKI, current therapies are nonspecific and supportive of the vital organ systems in the hope the kidney will recover. Read more

Supervisor: Prof S Satchell

Year round applications PhD Research Project Self-Funded PhD Students Only

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Enzyme-responsive peptide hydrogels as in situ forming long-acting drug delivery implants

Queen’s University Belfast School of Pharmacy

One of the key issues in the treatment and prevention of disease is that patients struggle to adhere to the complex dosage regimens of therapies, which often require multiple dosing at very specific times each day. Read more

Supervisor: Dr G Laverty

Year round applications PhD Research Project Self-Funded PhD Students Only

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Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

University of Leeds Faculty of Medicine and Health

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Supervisors: Dr F Errington-Mais, Dr V Jennings

Year round applications PhD Research Project Self-Funded PhD Students Only

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We have 223 in vivo PhD Projects, Programmes & Scholarships

in vivo PhD Projects, Programmes & Scholarships

We have 223 in vivo PhD Projects, Programmes & Scholarships

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