University of Hong Kong
Continue with FacebookLooking to list your PhD opportunities? Log in here.
We have 20 induced pluripotent stem cells PhD Projects, Programmes & Scholarships
induced pluripotent stem cells PhD Projects, Programmes & Scholarships
We have 20 induced pluripotent stem cells PhD Projects, Programmes & Scholarships
PhD saved successfully
An omics approach to understand and treat KMT2C-related neurodevelopmental disorder using induced pluripotent stem cells and CRISPR-Cas9
Background. We recently identified a novel human syndrome caused by mutations in a gene called KMT2C1. Patients with this condition predominantly have developmental delay and intellectual disability indicating the important function of this gene in brain’s normal development and function. Read more
Induced pluripotent stem cells (iPSCs) as model systems to study hematological malignancies
Myelodysplastic syndromes (MDS) are a type of blood cancer originating at the level of haematopoietic stem/progenitor cells (HSPCs) and often progress to acute myeloid leukaemia (AML). Read more
Stem cells and hungry neurons: neuropeptides in energy homeostasis
Summary. You will investigate the role of neural stem cells and neurons in energy homeostasis. You will determine how neuropeptides and diet affects stem cells, neurons and glia from mouse and human brain. Read more
PhD Studies with PACE – Protein and Cell Engineering Laboratory
PhD Studies with PACE – Protein and Cell Engineering Laboratory. “Tailored stem cell models to study and eventually cure degenerative diseases will be unlocked with engineered and enhanced biomolecules.”. Read more
Patient-Specific Stem Cells to Interrogate the Molecular Mechanism of Pain in Parkinson’s Disease
Parkinson's disease (PD) is a chronic, progressive neurodegenerative disease characterized by loss of nigrostriatal dopaminergic pathways. Read more
Identification of transcriptomic signatures of autism-like neurodevelopmental disorder
The overarching aim of this project is to define transcriptional patterns and identify new genetic elements essential for the correct development of the human brain. Read more
Investigating the role of endothelial cells in myelin damage in Alzheimer's diseases using iPSC-derived model
Alzheimer’s disease (AD) affects around 50 million people globally with no cure. Apart from well-known neuronal loss, myelin abnormalities in brain have been recently detected from early stage of AD. Read more
Stem Cells: Developing pluripotent stem cell models of inherited retinal diseases
Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide. Read more
Target enrichment of transposable elements for direct RNA sequencing
Commercial partner: Oxford Nanopore Technologies. Background. In our conventional understanding, we often assume that all cells in our body possess the same genetic information. Read more
Exploring the effect of hypoxia upon glioblastoma progression and response to treatments using a dynamic 3D iPSC-brain organoid
Background. Glioblastoma (GBM) is the most aggressive brain tumour, displaying considerable resistance to drug-/radiation-therapies. Read more
Deriving functional neurons from hIPSCs
Neuronal networks grown on petri dishes encode information as electrical activity. This activity is dictated by their underlying structural and functional connectivity. Read more
Establishing a choroid plexus organoid model for studying perinatal brain injury in preterm infants
Preterm infants, born at under 32-weeks gestation, are at risk of long-term neurodevelopmental impairment including cerebral palsy and compromised cortical development. Read more
Development of AI framework for iPSC image analysis and integration with transcriptomics
A fully funded PhD Studentship is available to work with Professor Viji Draviam, Professor of Quantitative Cell and Molecular Biology and Director of Industrial Innovation, School of Biological and Behavioural Science, Queen Mary University London, and Dr Victor Neduva, Senior Director, Genome and Biomarker Sciences, MSD. Read more
Epigenetic regulation in heart failure and cardiac sudden death
A large proportion of heart failure patients die from cardiac sudden death (SCD), a direct result of lethal ventricular arrhythmias, which is the principal cause of mortality from heart disease worldwide and remains a major unresolved public health problem. Read more
Epigenetic control of transcription factor regulation of adult neurogenesis in the dentate gyrus
In the adult brain, new neurons are continuously generated in the hippocampal dentate gyrus (DG). This neurogenesis process is highly regulated and consists of cell proliferation, neuronal differentiation, neuronal maturation and survival. Read more
- 1
- 2
