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We have 7 infertility PhD Projects, Programmes & Scholarships

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infertility PhD Projects, Programmes & Scholarships

We have 7 infertility PhD Projects, Programmes & Scholarships

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Calcium signalling in In-Vitro Fertilization: developing a non-invasive diagnostic tool using mathematical modelling and data analysis

IVF is the primary treatment of infertility with ~2.5 million treatments and ~500,000 births annually. The success rate has been ~25% for many decades but it has been decreasing while the IVF industry is projected to grow to 37.7 billion (USD) by 2027 with an ~10% annual growth rate. Read more
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Structural investigation of chromatin organisation in development

The genome of the fertilised zygote undergoes rapid remodelling in order to develop into a multicellular embryo. Of these events, the reprogramming of chromatin structure is essential to generate totipotency - the capacity to form the whole organism including all embryonic and extraembryonic cell types. Read more

Structure-based design of allosteric modulators for G protein-coupled receptors using molecular modelling and pharmacology experiments

Almost all physiological processes are regulated through the activation of G protein-coupled receptors (GPCRs). It has become widely accepted that most GPCRs possess binding sites spatially distinct from their natural ligand binding site (orthosteric site), termed as allosteric sites. Read more

Born Slippy: Understanding the tribological mechanisms of fertility treatments and their impact on conception

Infertility affects 186M women in the developed world, with approximately 55M attributed to tubal patency - this is a big problem! Hysterosalpingography or HSG is a diagnostic procedure that is also an effective treatment for tubal problems. Read more
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