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inflammation PhD Projects, Programs & Scholarships

We have 155 inflammation PhD Projects, Programs & Scholarships

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We have 155 inflammation PhD Projects, Programs & Scholarships

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(MRC DTP) Unravelling the role of microglial interleukin-1alpha on neuronal activity and functions during cerebrovascular inflammation after stroke

Interleukin-1 (IL-1) drives inflammation after stroke, contributing to brain damage and poorer outcome. Blocking IL-1 actions with the IL-1 receptor antagonist (IL-1Ra) is beneficial in pre-clinical stroke models, and studies in stroke patients show that IL-1Ra is safe and may improve clinical outcomes. Read more

Therapeutic targeting of chemokines in inflammation

Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more

Mitochondrial homeostasis and inflammation in Drosophila models of Parkinsons disease.

Neurodegenerative diseases such as Parkinson’s Disease are wide-spread, devastating and incurable. As over-65s are the fastest growing age-demographic, the need to better understand the molecular aetiology of these disorders is urgent. Read more

Mitochondrial homeostasis and inflammation in Drosophila models of Parkinsons disease.

Neurodegenerative diseases such as Parkinson’s Disease are wide-spread, devastating and incurable. As over-65s are the fastest growing age-demographic, the need to better understand the molecular aetiology of these disorders is urgent. Read more

The role of glucocorticoid desulfation in chronic inflammatory disease pathophysiology

Chronic inflammatory diseases (CIDs) are a common group of highly disabling immune conditions leading to persistent inflammation and tissue-specific manifestations, such as ulcerative colitis and arthritis. Read more

Understanding how inflammation affects brain disease

We know that both peripheral and central inflammation influence neurological disease. This influence progresses and worsens diverse brain diseases, but the mechanisms involved are poorly understood. Read more

Do Altered host-microbial interactions promote oral inflammation during ageing?

As we age, the systems of our bodies become less able to function; rendering people increasingly infirm. Ageing affects our immune system, impeding our ability to both fight infection and maintain tolerance. Read more

Pharmacological strategies to promote resolution of inflammation in disease

Inflammation plays a crucial role in the pathophysiological cascade of ischaemia reperfusion injury (I/RI), the incidence of which is extensive including myocardial infarction, stroke, peripheral artery disease, solid organ transplantation, sepsis, inflammatory bowel diseases, blood disorders (e.g. Read more

The role of neutrophil microvesicles in regulation of endothelial cell inflammation

Supervisor(s). Dr Victoria Ridger, Professor Endre Kiss-Toth and Professor Kong Peng Lam. Figures from the World Health Organisation show that cardiovascular disease (CVD) is the leading cause of death globally. Read more

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