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inhibitor PhD Projects, Programs & Scholarships

We have 31 inhibitor PhD Projects, Programs & Scholarships

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  Development and in-vitro testing of a urease inhibitor to prevent urinary catheter blockage
University of Bath Department of Chemistry
  Prof A T A Jenkins
Application Deadline: 31 March 2019
Introduction. the clinical problem. In the UK, approximately 15-25% of patients admitted to NHS hospitals each year will require urethral catheterisation.
Details
Type/Funding
  Defining the ‘molecular signature’ of PARP inhibitor sensitivity in blood cancers
Kingston University Faculty of Science, Engineering and Computing
  Dr T Gaymes
Applications accepted all year round
Despite significant advances in the understanding of the biology of blood cancers, identification of the most effective and safe form of treatment continues to present a formidable challenge to clinicians.
Details
Type/Funding
  Investigating the role of Inter-alpha-inhibitor Heavy Chain 3 in age-related macular degeneration
University of Manchester Faculty of Biology, Medicine and Health
  Dr S Clark, Prof T Day
Application Deadline: 31 March 2019
Age-related macular degeneration (AMD) is one of the leading causes of blindness globally. It is well established that although a multifactorial disease, AMD is largely genetically driven, with the majority of attributable genetic risk being associated with loci on chromosome 1 (Chr1) and chromosome 10 (Chr10).
Details
Type/Funding
  Medical Research Foundation National PhD Training Programme in Antimicrobial Resistance Research: Trade-offs between beta-lactam/beta-lactamase inhibitor resistance and fitness in enteric bacteria
University of Bristol School of Cellular and Molecular Medicine
  Prof M Avison, Dr A Herman, Dr M Williams, Dr J Spencer
Application Deadline: 31 March 2019
Beta-lactams are the most widely prescribed antimicrobial class worldwide. Resistance is primarily caused when bacteria produce beta-lactamase enzymes, of which there are many different types.
Details
Type/Funding
  Trade offs between beta-lactam/beta-lactamase inhibitor resistance and fitness in Enteric bacteria
University of Bristol School of Cellular and Molecular Medicine
  Prof M Avison, Dr J Spencer
Application Deadline: 31 March 2019
This studentship is open to Thai applicants only. Beta-lactams are the most widely prescribed antimicrobial class worldwide. Resistance is primarily caused when bacteria produce beta-lactamase enzymes, of which there are many different types.
Details
Type/Funding
  Synthetic Resistance to Potato Blight
University of Oxford Department of Plant Sciences
  Prof R Van der Hoorn
Applications accepted all year round
The oomycete potato pathogen Phytophthora infestans has caused devastation during the Irish Potato Famine in the 1840s. P. infestans still causes major problems in the potato industry, and is mostly controlled using agrochemicals.
Details
Type/Funding
  Medical Research Foundation National PhD Training Programme in Antimicrobial Resistance Research: Next Generation Inhibitors to Tackle Penicillin Resistance
University of Warwick School of Life Sciences
  Prof C G Dowson, Prof C Schofield
Application Deadline: 31 March 2019
Supervisors; Prof Christopher Dowson, Prof Chris Schofield. This project will involve the combination of biochemical assays, design, synthesis and testing the effectiveness of new inhibitors inspired by the mode of action of β-lactams.
Details
Type/Funding
  Analysis of intracellular sCTLA-4 and its contribution to intrinsic cell regulation
Aberdeen University School of Medicine, Medical Sciences & Nutrition
  Dr F J Ward, Dr R Abu Eid
Application Deadline: 29 March 2019
Cancer immunotherapy is among the most important recent developments in cancer treatment. Despite its impressive successes, however, the response in some patients is often limited and short lived.
Details
Type/Funding
  PhD in Dementia Research - Role of a mouse ortholog of CR1 (crry) in the 3xTG model of Alzheimer’s Disease (AD)
Cardiff University Cardiff School of Medicine
  Prof B Paul Morgan, Dr T Hughes
Application Deadline: 31 March 2019
Several genes of the pro-inflammatory complement system, including CR1, Cr1L, Clu and C3 have been linked to AD. However, there remains a yawning gap in our understanding of how proteins derived from these genes impact risk of AD.
Details
Type/Funding
  Novel drug target validation for treating Diabetes Mellitus (ref: SF18/APP/Soundararajan)
Northumbria University Faculty of Health and Life Sciences
  Dr M Soundararajan
Applications accepted all year round
The important cellular entities responsible for fighting against infections in our body are the T cells. T cells are however also shown to play a central role in the development of autoimmune diseases (AIDs) as “T cell activation hijacking” is the major autoimmune reaction causing mechanism observed in several AIDs.
Details
Type/Funding
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