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inhibitor PhD Projects, Programs & Scholarships

We have 31 inhibitor PhD Projects, Programs & Scholarships

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  Development and in-vitro testing of a urease inhibitor to prevent urinary catheter blockage
  Prof A T A Jenkins
Application Deadline: 31 March 2019
Introduction. the clinical problem. In the UK, approximately 15-25% of patients admitted to NHS hospitals each year will require urethral catheterisation.
  Defining the ‘molecular signature’ of PARP inhibitor sensitivity in blood cancers
  Dr T Gaymes
Applications accepted all year round
Despite significant advances in the understanding of the biology of blood cancers, identification of the most effective and safe form of treatment continues to present a formidable challenge to clinicians.
  Investigating the role of Inter-alpha-inhibitor Heavy Chain 3 in age-related macular degeneration
  Dr S Clark, Prof T Day
Application Deadline: 31 March 2019
Age-related macular degeneration (AMD) is one of the leading causes of blindness globally. It is well established that although a multifactorial disease, AMD is largely genetically driven, with the majority of attributable genetic risk being associated with loci on chromosome 1 (Chr1) and chromosome 10 (Chr10).
  Medical Research Foundation National PhD Training Programme in Antimicrobial Resistance Research: Trade-offs between beta-lactam/beta-lactamase inhibitor resistance and fitness in enteric bacteria
  Prof M Avison, Dr A Herman, Dr M Williams, Dr J Spencer
Application Deadline: 31 March 2019
Beta-lactams are the most widely prescribed antimicrobial class worldwide. Resistance is primarily caused when bacteria produce beta-lactamase enzymes, of which there are many different types.
  Trade offs between beta-lactam/beta-lactamase inhibitor resistance and fitness in Enteric bacteria
  Prof M Avison, Dr J Spencer
Application Deadline: 31 March 2019
This studentship is open to Thai applicants only. Beta-lactams are the most widely prescribed antimicrobial class worldwide. Resistance is primarily caused when bacteria produce beta-lactamase enzymes, of which there are many different types.
  Synthetic Resistance to Potato Blight
  Prof R Van der Hoorn
Applications accepted all year round
The oomycete potato pathogen Phytophthora infestans has caused devastation during the Irish Potato Famine in the 1840s. P. infestans still causes major problems in the potato industry, and is mostly controlled using agrochemicals.
  Medical Research Foundation National PhD Training Programme in Antimicrobial Resistance Research: Next Generation Inhibitors to Tackle Penicillin Resistance
  Prof C G Dowson, Prof C Schofield
Application Deadline: 31 March 2019
Supervisors; Prof Christopher Dowson, Prof Chris Schofield. This project will involve the combination of biochemical assays, design, synthesis and testing the effectiveness of new inhibitors inspired by the mode of action of β-lactams.
  Analysis of intracellular sCTLA-4 and its contribution to intrinsic cell regulation
  Dr F J Ward, Dr R Abu Eid
Application Deadline: 29 March 2019
Cancer immunotherapy is among the most important recent developments in cancer treatment. Despite its impressive successes, however, the response in some patients is often limited and short lived.
  PhD in Dementia Research - Role of a mouse ortholog of CR1 (crry) in the 3xTG model of Alzheimer’s Disease (AD)
  Prof B Paul Morgan, Dr T Hughes
Application Deadline: 31 March 2019
Several genes of the pro-inflammatory complement system, including CR1, Cr1L, Clu and C3 have been linked to AD. However, there remains a yawning gap in our understanding of how proteins derived from these genes impact risk of AD.
  Novel drug target validation for treating Diabetes Mellitus (ref: SF18/APP/Soundararajan)
  Dr M Soundararajan
Applications accepted all year round
The important cellular entities responsible for fighting against infections in our body are the T cells. T cells are however also shown to play a central role in the development of autoimmune diseases (AIDs) as “T cell activation hijacking” is the major autoimmune reaction causing mechanism observed in several AIDs.
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