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innate PhD Projects, Programs & Scholarships

We have 76 innate PhD Projects, Programs & Scholarships

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  Nucleic Acid Sensing: Investigating the molecular biology of activation and regulation of innate immune receptors that survey the cytosol, using a variety of virus infection models including influenza A virus, HIV and other retroviruses, flaviviruses such as Zika virus, and herpes viruses.
  Prof J Rehwinkel
Application Deadline: 11 January 2019
Investigating the molecular biology of activation and regulation of innate immune receptors that survey the cytosol, using a variety of virus infection models including influenza A virus, HIV and other retroviruses, flaviviruses such as Zika virus, and herpes viruses.
  Innate immune responses to influenza virus infection
  Prof E Fodor
Application Deadline: 11 January 2019
Influenza viruses are important human and animal pathogens; they cause widespread clinical and veterinary disease and have a considerable economic impact.
  Non-canonical signalling mechanisms in phagosome maturation
  Prof C E Eyers
Application Deadline: 11 January 2019
Phagosomes are intracellular vesicles that are formed by phagocytosing particles such as bacteria or apoptotic cells by specialised immune cells.
  Structure and Function of Innate Immune Signalling in Mosquito Vectors
  Research Group: Dr M Gangloff
  Dr M Gangloff
Applications accepted all year round
Over the course of a long evolutionary history vector-borne pathogens have developed mechanisms to successfully disrupt natural defences in both their mammalian hosts and insect vectors in order to survive and establish infection.
  Global analysis of evasive strategies developed by Staphylococcus aureus to circumvent complement and innate immunity
  Dr M Laabei
Application Deadline: 24 February 2019
Staphylococcus aureus is an important human pathogen responsible for a wide-spectrum of diseases that range from mild superficial skin diseases to life-threatening infections.
  Cryo electron microscopy to study innate immune complexes on the surface of cancer cells
  Dr J Emsley
Application Deadline: 31 May 2019
Blood vessels of tumors carry specific markers on the cell surface. The innate immune system consisting of complement proteins and white blood cells (macrophages) are involved in the recognition and destruction of cancer cells.
  MRC DiMeN Doctoral Training Partnership: How do superbugs hide from the host? Understanding the mechanisms of innate immune evasion in the opportunistic pathogen Enterococcus faecalis
  Dr S Mesnage, Dr P Elks
Application Deadline: 21 January 2019
All enterococci produce a surface polysaccharide called the enterococcal polysaccharide antigen (EPA) that plays a key role during pathogenesis (Mistou et al., 2016).
  MRC DiMeN Doctoral Training Partnership: How do superbugs hide from the host? Understanding the mechanisms of innate immune evasion in the opportunistic pathogen Enterococcus faecalis
  Dr S Mesnage, Dr P Elks
Application Deadline: 21 January 2019
All enterococci produce a surface polysaccharide called the enterococcal polysaccharide antigen (EPA) that plays a key role during pathogenesis (Mistou et al., 2016).
  Exploring aberrant inflammasome activation in chronic granulomatous disease
  Dr S Webster, Prof C E Bryant
Applications accepted all year round
This project will test the hypothesis. Aberrant inflammasome activation can be caused by mitochondrial ROS mediated NLRP3 inflammasome activation.
  MRC DiMeN Doctoral Training Partnership: Determination of how killer pathogenic fungi evade human innate immune defences
  Prof J Quinn, Dr S Johnston
Application Deadline: 21 January 2019
More people die from fungal infections than from malaria, tuberculosis, or ‘superbugs’ such as MRSA. Candida species are an important group of human fungal pathogens causing over 400,000 life threatening infections per year.
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