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intellectual disability PhD Projects, Programs & Scholarships

We have 4 intellectual disability PhD Projects, Programs & Scholarships

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  (MRC DTP) Understanding the mechanism and finding treatment of neurodevelopmental disorder caused by KMT2C mutations
  Dr S Banka, Prof S J Kimber
Application Deadline: 15 November 2019

Funding Type

PhD Type

Background. We recently identified a novel human syndrome caused by mutations in a gene called KMT2C1. Patients with this condition predominantly have developmental delay and intellectual disability indicating the important function of this gene in brain’s normal development and function.
  Studying the Molecular Mechanism of Mitochondrial Aminoacyl tRNA Synthetases in Neurons
  Dr R Horvath, Prof P Chinnery
Application Deadline: 3 December 2019

Funding Type

PhD Type

Aminoacyl-tRNA synthetases (ARSs) are essential and ubiquitous ‘house-keeping’ enzymes responsible for charging amino acids to their cognate tRNAs and provide the substrates for global protein synthesis in the cytosol and mitochondria.
  Gene Regulation by the KAT6A/MOZ Histone Acetyltransferase
  Prof D Heery
Applications accepted all year round

Funding Type

PhD Type

The human KAT6A and KAT6B genes encode the nuclear proteins MOZ and MORF, which are key gene regulators in development of blood, brain and other tissues.
  Molecular dissection of protein palmitoylation in neurons
  Dr M Collins
Applications accepted all year round

Funding Type

PhD Type

Palmitoylation (S-acylation), the only known reversible lipid modification of proteins, is an important regulator of protein localisation and function.
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