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ion channel PhD Projects, Programs & Scholarships

We have 22 ion channel PhD Projects, Programs & Scholarships

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  Ion channel gating kinetics and structure implication for drug delivery
University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr Z Hughes
Applications accepted all year round
Ion channels are proteins which sit in the membrane of every cell in the body and control the flow of positively charged ions such as sodium and potassium into and out of the cell.
Details
Type/Funding
  Development and characterisation of synthetic ion channel binding proteins.
University of Leeds Faculty of Biological Sciences
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr D Tomlinson
Applications accepted all year round
We are developing methods to identify novel proteins, Affimers, that recognise extracellular domains of ion channels. These have applications in various aspects of biology, from tools to visualise the location and distribution of ion channels in native tissue, to novel modulators of ion channel function.
Details
Type/Funding
  Exploring the effects of decanoic acid on ion channel function and synaptic network activity
Royal Holloway, University of London School of Biological Sciences
  Dr P Chen, Prof R S B Williams
Application Deadline: 15 January 2019
Most anti epileptic drugs modify synaptic transmission or neuronal excitability and act on ionotropic receptors for the main excitatory (glutamate) or inhibitory (GABA) neurotransmitters or ion channels within the mammalian CNS.
Details
Type/Funding
  Heme regulation of signalling at potassium channels in the cardiovascular system
University of Leicester Molecular and Cell Biology
  Dr N Storey, Dr N W Davies
Application Deadline: 6 January 2019
Ion channels in the smooth muscle of the cardiovascular system control blood pressure and cardiac contractility through changes in their membrane potential.
Details
Type/Funding
  Ion channel regulation in models of neurodegeneration
University of Reading School of Pharmacy
  Dr M Dallas, Prof G J Stephens, Dr A Bithell
Applications accepted all year round
Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated.
Details
Type/Funding
  Ion channel clustering in neuronal membranes
University of Manchester Faculty of Biology, Medicine and Health
  Dr S M Prince, Prof R Ford
Applications accepted all year round
The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions.
Details
Type/Funding
  Wellcome Trust 4-year Doctoral Programme in Ion Channels and Membrane Transport in Health and Disease (OXION)
University of Oxford Medical Sciences Doctoral Training Centre
Wellcome Trust 4-year Doctoral Programme in Ion Channels and Membrane Transport in Health and Disease (OXION). OXION is an Oxford-based consortium of world-leading scientists with a general interest in the role of ion channels and membrane transport in health and disease.
Details
Type/Funding
  Tissue Engineering of Functional Cardiac Tissue using a Newly Characterised Cardiac Stem Cell Population
University of Liverpool Institute of Ageing and Chronic Disease
  Dr R Oldershaw, Dr R Barrett-Jolley, Dr A P Meeson
Applications accepted all year round
We will develop a novel route to create and test stem cell-derived engineered cardiac tissue for use in heart infarct repair or in vitro drug screening.
Details
Type/Funding
  A computational and mechanistic study of sodium-activated potassium channel function
University of Leeds Faculty of Biological Sciences
  Research Group: BBSRC White Rose DTP
  Dr J D Lippiat, Dr A Kalli, Dr S Muench
Application Deadline: 7 January 2019
The sodium-activated potassium channel KNa1.1 (KCNT1, Slack, Slo2.2) is found in neurons and its function is to conduct ions across neuronal membranes.
Details
Type/Funding
  Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure
University of Bradford Faculty of Life Sciences
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr M H Brinkworth, Prof D Anderson
Applications accepted all year round
Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.
Details
Type/Funding
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