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ion channel PhD Projects, Programs & Scholarships

We have 22 ion channel PhD Projects, Programs & Scholarships

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  Ion channel gating kinetics and structure implication for drug delivery
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr Z Hughes
Applications accepted all year round
Ion channels are proteins which sit in the membrane of every cell in the body and control the flow of positively charged ions such as sodium and potassium into and out of the cell.
  Development and characterisation of synthetic ion channel binding proteins.
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr D Tomlinson
Applications accepted all year round
We are developing methods to identify novel proteins, Affimers, that recognise extracellular domains of ion channels. These have applications in various aspects of biology, from tools to visualise the location and distribution of ion channels in native tissue, to novel modulators of ion channel function.
  Exploring the effects of decanoic acid on ion channel function and synaptic network activity
  Dr P Chen, Prof R S B Williams
Application Deadline: 15 January 2019
Most anti epileptic drugs modify synaptic transmission or neuronal excitability and act on ionotropic receptors for the main excitatory (glutamate) or inhibitory (GABA) neurotransmitters or ion channels within the mammalian CNS.
  Heme regulation of signalling at potassium channels in the cardiovascular system
  Dr N Storey, Dr N W Davies
Application Deadline: 6 January 2019
Ion channels in the smooth muscle of the cardiovascular system control blood pressure and cardiac contractility through changes in their membrane potential.
  Ion channel regulation in models of neurodegeneration
  Dr M Dallas, Prof G J Stephens, Dr A Bithell
Applications accepted all year round
Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated.
  Ion channel clustering in neuronal membranes
  Dr S M Prince, Prof R Ford
Applications accepted all year round
The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions.
  Wellcome Trust 4-year Doctoral Programme in Ion Channels and Membrane Transport in Health and Disease (OXION)
Wellcome Trust 4-year Doctoral Programme in Ion Channels and Membrane Transport in Health and Disease (OXION). OXION is an Oxford-based consortium of world-leading scientists with a general interest in the role of ion channels and membrane transport in health and disease.
  Tissue Engineering of Functional Cardiac Tissue using a Newly Characterised Cardiac Stem Cell Population
  Dr R Oldershaw, Dr R Barrett-Jolley, Dr A P Meeson
Applications accepted all year round
We will develop a novel route to create and test stem cell-derived engineered cardiac tissue for use in heart infarct repair or in vitro drug screening.
  A computational and mechanistic study of sodium-activated potassium channel function
  Research Group: BBSRC White Rose DTP
  Dr J D Lippiat, Dr A Kalli, Dr S Muench
Application Deadline: 7 January 2019
The sodium-activated potassium channel KNa1.1 (KCNT1, Slack, Slo2.2) is found in neurons and its function is to conduct ions across neuronal membranes.
  Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr M H Brinkworth, Prof D Anderson
Applications accepted all year round
Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.
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