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ion channels PhD Projects, Programs & Scholarships

We have 20 ion channels PhD Projects, Programs & Scholarships

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  The role of the Exocyst complex in trafficking ion channels in polarised epithelia
  Dr K Hamilton, Prof F McDonald
Applications accepted all year round
Associate Professor Kirk L. Hamilton and Associate Professor Fiona J. McDonald. Proper trafficking of ion channels in epithelia is key to epithelial cell function.
  PhD Studentship Opportunity in Investigation of quantum coherent transport and EM field sensitivity of ion channel transport of neuronal cells
  Dr K Jeevaratnam, Prof J J Mcfadden, Dr R Lewis, Prof S Silva
Application Deadline: 30 April 2019
Nerve ion channels play a crucial role in brain function as nerve firing is triggering by the opening and closing of ion channels that allow current of molecular ions to flow in and out of neurons, triggering the action potential travels along nerves.
  Natural toxins and their synthetic analogues as tools to study ion channels and as potential drugs and pesticides
  Dr I R Mellor
Applications accepted all year round
The project will use a combination of electrophysiological techniques such as voltage-clamp and patch-clamp with molecular biology and protein expression to understand how natural toxins and their synthetic analogues act on ion channels in the nervous system.
  Electrophysiological changes in ion channels in human haploid and diploid (spermatozoa and lymphocytes) after nanoparticle exposure
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr M H Brinkworth, Prof D Anderson
Applications accepted all year round
Nanomaterial-mediated delivery represents a promising technique for repro- and geno- toxicology with a potential to improve the safety and efficacy of existing methodologies, including experimental gene therapy and sperm-mediated gene transfer.
  The mechanism of gating and transport of pentameric Magnesium ion channels
  Dr S M Prince, Prof R Ford
Applications accepted all year round
Magnesium ions are a co-factor in many important biological processes particularly because of the requirement for Mg2+ in the hydrolysis of Adenosine tri-phosphate, the ubiquitous cellular energy source.
  Ion channel gating kinetics and structure implication for drug delivery
  Research Group: Chemistry and Biosciences
  Dr L Shang, Dr Z Hughes
Applications accepted all year round
Ion channels are proteins which sit in the membrane of every cell in the body and control the flow of positively charged ions such as sodium and potassium into and out of the cell.
  Development and characterisation of synthetic ion channel binding proteins.
  Research Group: School of Biomedical Sciences
  Dr J D Lippiat, Dr D Tomlinson
Applications accepted all year round
We are developing methods to identify novel proteins, Affimers, that recognise extracellular domains of ion channels. These have applications in various aspects of biology, from tools to visualise the location and distribution of ion channels in native tissue, to novel modulators of ion channel function.
  Ion channel regulation in models of neurodegeneration
  Dr M Dallas, Prof G J Stephens, Dr A Bithell
Applications accepted all year round
Ion channels are important regulators of cellular physiology. There is now growing awareness that these proteins are invovled in pathological states, with relation to neurodegeneration voltage-gated potassium and voltage-gated calicum channels have been implicated.
  Investigating the role of the mechanosensor channel Piezo1 in human disease
  Dr K Erdmann
Applications accepted all year round
Piezo proteins are ion channels that are gated by mechanical stimuli like stretch or shear stress. In mammalians there are two Piezo isoforms (Piezo1 and Piezo2) with largely different expression pattern.
  Ion channel clustering in neuronal membranes
  Dr S M Prince, Prof R Ford
Applications accepted all year round
The aim of the study is to investigate the organization of ion channels in the membranes of excitable cells by scaffold proteins, and to discover how the properties of the channels are modified by these interactions.
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