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ips PhD Projects, Programs & Scholarships

We have 14 ips PhD Projects, Programs & Scholarships

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  Harnessing stem cells to develop regenerative therapies for childhood heart disease.
  Dr E Porrello, Dr D Elliott
Applications accepted all year round
LABORATORY OVERVIEW. The Cardiac Regeneration Laboratory is seeking highly motivated PhD students to work on a project related to understanding the underlying causes of congenital heart disease and developing novel regenerative therapies.
  Using CRISPR in iPS cells to modify platelet function
  Dr C.E. Hughes
Applications accepted all year round
"Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus.
  MRC DiMeN Doctoral Training Partnership: How interferon defends the brain against viral invasion
  Dr C Duncan, Prof S Hambleton, Dr D Rico, Prof W S James
Application Deadline: 21 January 2019
Contrary to the perception of the brain as an ‘immune-privileged’ organ, it is now clear that the brain engages a potent immune signalling network to defend itself against viral infection (encephalitis).
  Influence of underlying matrix on induced pluripotent stem cell differentiation and integration of trabecular meshwork cells
  Dr CM Sheridan, Dr R Oldershaw
Applications accepted all year round
There is an urgent need for further treatment options for the blinding condition of Glaucoma Unfortunately with age there is a progressive loss of cells (Trabecular meshwork) from the eye’s outflow pathway which is even more severe with patients with glaucoma.
  From Hematopoietic development towards generation of Hematopoietic stem cells
  Research Group: Institute of Stem Cell Research
  Prof A Medvinsky, Dr V Wilson
Application Deadline: 13 December 2018
Haematopoietic stem cells (HSCs) give rise to the majority of cells in the adult haematopoietic system, however, their embryonic development is poorly understood.
  Understanding transcription mediated methylation of intragenic CpG islands in health and disease
  Dr C Tufarelli, Prof S Cowley
Application Deadline: 6 January 2019
1. Project outline describing the scientific rationale of the project (max 4,000 characters incl. spaces and returns). DNA methylation is an epigenetic modification that affects gene expression without altering gene sequences.
  Understanding Neuroinflammation through advanced in vitro 3D modelling using human Pluripotent Stem Cells
  Dr S Cowley, Prof W S James
Application Deadline: 25 January 2019
Microglia - brain-resident macrophages - carry out homeostatic surveillance functions in the brain, clearing dying cells, extracellular debris, and pruning synapses during development.
  The importance of the DNA damage response in neurodegeneration
  Dr R Tuxworth
Applications accepted all year round
DNA damage occurs in early-stage neurodegenerative diseases. The response of neurons to the damage may contribute to disease progression by inducing senescence, cell-cycle and apoptosis.
  Understanding how the NuRD complex regulates 3D genome organization using a combination of single-molecule super-resolution imaging and single cell biology
  Prof E D Laue
Applications accepted all year round
The spatial organisation of the genome is known to play an important role in regulating RNA transcription to effect cell-type-specific gene expression programs, and to control the differentiation of embryonic stem (ES) cells.
  4 Year Wellcome Trust PhD Programme: Functions & Applications of a Novel Embryonic Stem Cell Signalling Pathway
  Dr GM Findlay
Application Deadline: 14 December 2018
The Findlay lab employs cutting-edge technologies to unravel Embryonic Stem (ES) cell signalling networks (Williams et al, Cell Rep 2016, Fernandez-Alonso et al, EMBO Rep 2017; Bustos et al, Cell Rep 2018), culminating in our recent discovery of the ERK5 pathway as an exciting new regulator of ES cell pluripotency.
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