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ips PhD Projects, Programmes & Scholarships
We have 8 ips PhD Projects, Programmes & Scholarships
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MSc by Research: Regulation of the stability of the Notch intracellular domain in iPS derived presomitic mesoderm cells
Notch is one of the major highly conserved signalling pathways that regulate cell-cell communication which involves gene regulation mechanisms that control multiple processes during development and adult life. Read more
Using CRISPR in iPS cells to modify platelet function
Platelets are the small cells in the blood whose job it is to prevent bleeding. Under normal conditions, when they encounter a damaged blood vessel they become activated and form a thrombus. Read more
Screening of chemical libraries using iPS models for investigating the role of prion protein in Alzheimer’s disease
Background. AD has been identified as a protein misfolding disease (proteopathy). The disease is caused by accumulation of two major amyloids. Read more
Targeting the ‘Worst of the Worst’ – developing novel treatments for Poor Outcome Triple Negative Breast Cancers.
We will investigate biology driving the aggressive features of Poor Outcome Triple Negative Breast Cancers (PO-TNBCs). PO-TNBCs possess the worst outcomes amongst all breast cancers, with high rates of metastases and chemoresistance. Read more
Generating human diabetic blood vessel organoids as a powerful model to investigate and treat the diabetic vasculopathy
In this project induced pluripotent stem cells will be derived diabetic patient specific blood vessel organoids. Read more
MSc by Research: Function of presomitic mesoderm specific phosphorylation of the Notch intracellular domain in somitogenesis
The Notch signalling pathway is one of the key pathways required for the developing embryo. It is especially important for the process of somitogenesis, the formation of body segments that develop into e.g. Read more
Bioengineering a full thickness cornea
Corneal blindness is the 4th leading cause of global blindness (WHO). Corneal scarring can be caused by trauma or infection and corneal replacement with donor corneas or synthetic (plastic) alternatives is currently the sole treatment to restore vision. Read more
Privacy-preserving Outsourced Computation
The Centre for Doctoral Training in Cyber Security for the Everyday seeks to recruit a PhD student to work on practical privacy-preserving outsourced computation techniques, such as homomorphic encryption (HE). Read more
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