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ipsc PhD Projects, Programs & Scholarships

We have 12 ipsc PhD Projects, Programs & Scholarships

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  Induced pluripotent stem-cell (iPSC) reprogramming in bone and blood cancers (Ref:SF20/APP/PAL)
  Dr D Pal
Applications accepted all year round

Funding Type

PhD Type

iPSC (somatic cells reprogrammed to an embryonic-stem-cell-like state) are not only a means of patient relevant disease modelling, but de-differentiation of terminal cells to their primitive precursors often reveal aberrations in tissue development.
  Characterisation of the neuronal receptor for soluble amyloid precursor protein: a route to new therapeutic targets for Alzheimer’s disease
  Prof N Hooper, Prof M J Humphries
Applications accepted all year round

Funding Type

PhD Type

Alzheimer’s disease (AD) is the commonest form of dementia for which currently there is no means of stopping or even slowing the disease.
  Generation of transplant tissue following correction of patient stem cells by genomic engineering
  Dr F Manson, Dr RL Taylor, Dr A Adamson
Applications accepted all year round

Funding Type

PhD Type

A number of retinal degenerations result from mutations in genes expressed in the retinal pigment epithelium (RPE) which lies under the photoreceptors.
  Genetics of inherited cardiovascular disease: Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Prof H Watkins, Prof H Ashrafian, Prof C Redwood, Prof M Farrall
Application Deadline: 24 July 2020

Funding Type

PhD Type

I have had a longstanding focus on inherited heart muscle diseases, in particular hypertrophic cardiomyopathy, which is a relatively common Mendelian condition which puts affected individuals at risk of sudden cardiac death.
  Targeting metabolic vulnerabilities in human prostate cancer
  Dr R Heer
Application Deadline: 22 April 2020

Funding Type

PhD Type

Number of awards. 1. Start date and duration. 28 September 2020. Overview. Prostate cancer is strongly associated with ageing and a major clinical problem for older men.
  Therapeutic models for Spinal muscular atrophy
  Prof R Yáñez-Muñoz
Applications accepted all year round

Funding Type

PhD Type

Our laboratory works on Gene Therapy in the Central Nervous System and Gene Repair, using novel viral vectors, gene targeting and induced pluripotent stem cells (iPSCs) as core technologies.
  Development of iPSCs from patients with Urofacial Syndrome for disease modelling
  Prof S J Kimber, Prof A Woolf
Applications accepted all year round

Funding Type

PhD Type

Peripheral neuropathies (PNs) affect 2% of the general population. Somatic PNs cause locomotor and sensory deficits, while autonomic PNs cause cardiac dysrhythmias and gastrointestinal and urinary bladder dysfunction.
  Autophagy and neuroinflammation in Parkinson’s
  Dr J D Lane
Applications accepted all year round

Funding Type

PhD Type

Autophagy is an essential catabolic process that protects cells against diverse stresses. Autophagy prevents many human diseases including neurodegeneration, so a complete understanding of this process is needed.
  MSc by Research Programme: ADP-ribosylation in the aging nervous system
  Dr L McGurk
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Developing pluripotent stem cell models of inherited retinal diseases
  Prof C A Johnson
Applications accepted all year round

Funding Type

PhD Type

Background. Inherited retinal dystrophies are a leading cause of blindness and visual loss in the UK working age population. However, despite the widespread diagnostic use of next-generation sequencing, a molecular genetic diagnosis is unavailable for many patients world-wide.
  Development of the hematopoietic/ immune system in the embryo
  Prof M DeBruijn
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
  Development of the hematopoietic/ immune system in the embryo
  Prof M DeBruijn
Application Deadline: 24 July 2020

Funding Type

PhD Type

Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
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