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ipsc PhD Projects, Programs & Scholarships

We have 9 ipsc PhD Projects, Programs & Scholarships

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  Molecular pathogenesis of the myelodysplastic syndromes: investigation of the molecular mechanisms involved in disease initiation and progression in the myeloid malignancy myelodysplastic syndromes (MDS)
  Dr J Boultwood, Dr A Pellagatti
Application Deadline: 26 July 2019
The main focus of our group is the investigation of the molecular mechanisms involved in disease initiation and progression in the myeloid malignancy myelodysplastic syndromes (MDS).
  Efficacy testing of biomaterial delivered iPS cells in in vitro cultures systems to mimic the degenerate niche
  Prof C Le Maitre, Prof C Sammon
Application Deadline: 31 May 2019
Low back pain (LBP) is a leading cause of disability and morbidity worldwide. It is widely accepted that a major contributor to LBP is intervertebral disc degeneration (IDD).
  Generation of transplant tissue following correction of patient stem cells by genomic engineering
  Dr F Manson, Dr RL Taylor, Dr A Adamson
Applications accepted all year round
A number of retinal degenerations result from mutations in genes expressed in the retinal pigment epithelium (RPE) which lies under the photoreceptors.
  Therapeutic models for Spinal muscular atrophy
  Prof R Yáñez-Muñoz
Applications accepted all year round
Our laboratory works on Gene Therapy in the Central Nervous System and Gene Repair, using novel viral vectors, gene targeting and induced pluripotent stem cells (iPSCs) as core technologies.
  Investigations into the neuroprotective actions of leptin and leptin-based mimetics in models of tauopathy.
  Dr J Harvey
Applications accepted all year round
In neurodegenerative disorders like Alzheimer’s disease (AD), synaptic communication within brain networks are impaired leading to significant memory deficits and dementia.
  Development of iPSCs from patients with Urofacial Syndrome for disease modelling
  Prof S J Kimber, Prof A Woolf
Applications accepted all year round
Peripheral neuropathies (PNs) affect 2% of the general population. Somatic PNs cause locomotor and sensory deficits, while autonomic PNs cause cardiac dysrhythmias and gastrointestinal and urinary bladder dysfunction.
  Development of the hematopoietic/ immune system in the embryo: obtaining a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development
  Prof M DeBruijn
Application Deadline: 26 July 2019
Development of the hematopoietic/ immune system in the embryo. Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
  Genetics of inherited cardiovascular disease: Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Prof H Watkins, Prof H Ashrafian, Prof C Redwood, Prof M Farrall
Application Deadline: 26 July 2019
Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
  Genomics of Diabetes: Functional characterisation of T2D GWAS
  Dr A Gloyn
Application Deadline: 26 July 2019
Diabetes already affects 415 million people worldwide. In the UK, there will be 5M people with type 2 diabetes (T2D) by 2025, accounting for 1 in 30 prescriptions and £25 billion in annual NHS costs.
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