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ipsc PhD Projects, Programs & Scholarships

We have 9 ipsc PhD Projects, Programs & Scholarships

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  Molecular pathogenesis of the myelodysplastic syndromes: investigation of the molecular mechanisms involved in disease initiation and progression in the myeloid malignancy myelodysplastic syndromes (MDS)
University of Oxford Radcliffe Department of Medicine
  Dr J Boultwood, Dr A Pellagatti
Application Deadline: 26 July 2019
The main focus of our group is the investigation of the molecular mechanisms involved in disease initiation and progression in the myeloid malignancy myelodysplastic syndromes (MDS).
Details
Type/Funding
  Efficacy testing of biomaterial delivered iPS cells in in vitro cultures systems to mimic the degenerate niche
Sheffield Hallam University Biomolecular Sciences Research Centre
  Prof C Le Maitre, Prof C Sammon
Application Deadline: 31 May 2019
Low back pain (LBP) is a leading cause of disability and morbidity worldwide. It is widely accepted that a major contributor to LBP is intervertebral disc degeneration (IDD).
Details
Type/Funding
  Generation of transplant tissue following correction of patient stem cells by genomic engineering
University of Manchester Faculty of Biology, Medicine and Health
  Dr F Manson, Dr RL Taylor, Dr A Adamson
Applications accepted all year round
A number of retinal degenerations result from mutations in genes expressed in the retinal pigment epithelium (RPE) which lies under the photoreceptors.
Details
Type/Funding
  Therapeutic models for Spinal muscular atrophy
Royal Holloway, University of London School of Biological Sciences
  Prof R Yáñez-Muñoz
Applications accepted all year round
Our laboratory works on Gene Therapy in the Central Nervous System and Gene Repair, using novel viral vectors, gene targeting and induced pluripotent stem cells (iPSCs) as core technologies.
Details
Type/Funding
  Investigations into the neuroprotective actions of leptin and leptin-based mimetics in models of tauopathy.
University of Dundee School of Medicine
  Dr J Harvey
Applications accepted all year round
In neurodegenerative disorders like Alzheimer’s disease (AD), synaptic communication within brain networks are impaired leading to significant memory deficits and dementia.
Details
Type/Funding
  Development of iPSCs from patients with Urofacial Syndrome for disease modelling
University of Manchester Faculty of Biology, Medicine and Health
  Prof S J Kimber, Prof A Woolf
Applications accepted all year round
Peripheral neuropathies (PNs) affect 2% of the general population. Somatic PNs cause locomotor and sensory deficits, while autonomic PNs cause cardiac dysrhythmias and gastrointestinal and urinary bladder dysfunction.
Details
Type/Funding
  Development of the hematopoietic/ immune system in the embryo: obtaining a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development
University of Oxford Radcliffe Department of Medicine
  Prof M DeBruijn
Application Deadline: 26 July 2019
Development of the hematopoietic/ immune system in the embryo. Our aim is to obtain a mechanistic insight into the birth of hematopoietic stem and progenitor cells in embryonic development and determine the contribution of these cells to the emerging hematopoietic and immune systems of the embryo.
Details
Type/Funding
  Genetics of inherited cardiovascular disease: Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
University of Oxford Radcliffe Department of Medicine
  Prof H Watkins, Prof H Ashrafian, Prof C Redwood, Prof M Farrall
Application Deadline: 26 July 2019
Using molecular genetic analysis of cardiovascular disease as a tool to define disease mechanisms and therapeutic targets.
Details
Type/Funding
  Genomics of Diabetes: Functional characterisation of T2D GWAS
University of Oxford Radcliffe Department of Medicine
  Dr A Gloyn
Application Deadline: 26 July 2019
Diabetes already affects 415 million people worldwide. In the UK, there will be 5M people with type 2 diabetes (T2D) by 2025, accounting for 1 in 30 prescriptions and £25 billion in annual NHS costs.
Details
Type/Funding
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