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kcl MRC PhD Projects, Programmes & Scholarships
We have 7 kcl MRC PhD Projects, Programmes & Scholarships
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Engineering Nanoparticles for prenatal applications
We aim to understand how prenatal therapy can be used to treat sickle cell disease (SCD) by developing a nanoparticle delivery system to encapsulate gene-editing tools in human and mouse fetal haematopoietic stem cells (HSCs) and delivery methods in a mouse model of SCD. Read more
Evaluation of the quantitative accuracy and radiation dosimetry of an advanced pre-clinical multipinhole SPECT/CT theranostic imaging device
Radionuclide-based theranostics, where targeted diagnostic and therapeutic radiopharmaceuticals are combined for precision treatment of cancer, has revolutionised nuclear medicine. Read more
Better localisation for epilepsy surgery by optimising simultaneous EEG and functional MRI recordings at 7T
For adults and children with focal epilepsy, surgical removal of the brain region responsible for seizure generation is the only possible complete cure. Read more
Elucidating spatio-temporal nuclear dynamics in 4D using state-of-the-art imaging in beating hearts
Traditionally, a cell’s nucleus has been regarded as a passive organelle that stores and protects the genome, facilitating transcription and replication. Read more
Trans-generational transmission of obesity and obesity-induced liver disease: a role for maternal microbiota and Toll-like receptors
The United Kingdom adult population prevalence of obesity is 30%. The children statistics are similarly alarming with 30% of children, overweight or obese. Read more
Interrogating the therapeutic impact of MYB overdose brought on by AKT inhibitor treatment in blood cancers
Oncogene addiction is defined as the unusual dependence of certain cancer cells to the activity of aberrantly activated gene products. Read more
Optimization of the Potency and Specificity of Engineered Regulatory T Cells to Treat Inflammatory and Fibrotic Liver Diseases
The prevalence of chronic liver disease, the 5th most common cause of death in the UK is rising sharply mainly due to the increasing load of viral hepatitis, alcohol- related liver disease and non-alcoholic fatty liver. Read more
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