Molecular role of Bruton's Tyrosine Kinase (BTK) in the NLRP3 Inflammasome
Prof A Weber
30 January 2019
Topic. The NLRP3 inflammasome is a multi-protein complex driving inflammation upon exogenous and endogenous (sterile) insults during infection, tissue damage or cellular stress and its assembly has been considered a key process in initiating inflammation.
The role of hnRNPUL proteins in the DNA damage response.
Dr R J A Grand, Dr G Stewart
Applications accepted all year round
Applications Open to. Someone who is very highly committed to scientific research with a 2.1 or equivalent degree in a science subject and can provide their own funding.
(BBSRC DTP) Inhibition of SR protein kinase 1 with designer peptides
Dr A Golovanov, Dr A Almond
31 January 2019
This PhD project addresses BBSRC’s ENWW in that the student will be trained in. Biophysical techniques - ITC, SPR, CD; Structural biology techniques - solution state NMR and X-ray crystallography; Computational techniques - molecular dynamics simulations and computer modelling and analysis.