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kinase PhD Projects, Programs & Scholarships

We have 47 kinase PhD Projects, Programs & Scholarships

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  Using single molecule spectroscopy to determine the drivers of conformational change in protein kinases
  Dr C Dodson
Applications accepted all year round

Funding Type

PhD Type

Protein kinases are central to many cellular processes (eg cell division and the response to external signals) and are current drug targets in cancer, cardiac and inflammatory disease.
  Centrosome Amplification and Cancer
  Dr Y Ching
Applications accepted all year round

Funding Type

PhD Type

Centrosome, which is the microtubule-organising center (MTOC) in the cell, plays a critical role in determining the motility, polarity and division of cell.
  Unravelling the oncogenic activities of serum- and glucocorticoid-regulated kinase 1 (SGK1)
  Dr K Brown
Applications accepted all year round

Funding Type

PhD Type

The phosphoinositide 3-kinase (PI3K) pathway is a master regulator of numerous cellular phenotypes associated with cancer including cell survival, proliferation, growth, altered metabolism and malignant transformation.
  MSc by Research Programme: LRRK2 kinase pathway activation during infection
  Dr E Sammler
Application Deadline: 16 July 2020

Funding Type

PhD Type

This course allows you to work alongside our world renowned experts from the School of Life Sciences and gain a ’real research’ experience.
  Cardiac energetics and integrative physiology: Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Prof C Lygate, Dr S Zervou
Application Deadline: 24 July 2020

Funding Type

PhD Type

Studying key components of the creatine kinase system to understand how they contribute to the pathophysiology of ischaemic heart disease and chronic heart failure.
  Cardiotoxicity of cancer drugs targeting the extracellular signal-regulated kinase 1/2 (ERK1/2) cascade
  Prof A Clerk
Applications accepted all year round

Funding Type

PhD Type

"Heart failure is a leading cause of morbidity and mortality worldwide. The contractile cells of the heart, cardiomyocytes, possess many protective mechanisms, allowing them to withstand pathophysiological stresses.
  PhD Studentship Opportunity in the Role of Calcium Calmodulin Kinase II in modulating lipid metabolism in the articular cartilage and osteoarthritis
  Dr G Nalesso, Dr B Fielding
Application Deadline: 31 May 2020

Funding Type

PhD Type

Osteoarthritis (OA), is a major musculoskeletal condition affecting 240 million people worldwide for which no cure exists other than symptomatic relief and surgical joint replacement.
  Tyrosine kinase inhibitors conjugated tumour targeting dyes for the treatment of glioblastoma.
  Dr J Jose, Dr P Choi
Applications accepted all year round

Funding Type

PhD Type

Glioblastoma (GBM) remains a lethal and difficult to treat cancer with a dismal outcome. Although we have a better understanding of the disease progression, a concurrent increase in therapeutic intervention is lagging.
  Characterisation of cell death pathways upon activation of the endoplasmic reticulum stress sensor IRE1alpha
  Dr M Schroeder
Applications accepted all year round

Funding Type

PhD Type

A self-funded PhD project to investigate cell death pathways activated by endoplasmic reticulum (ER) stress is available in the group of Dr.
  The functions of the Class II Pi3-kinase signals in vivo
  Dr L MacDougall, Dr M Baron
Applications accepted all year round

Funding Type

PhD Type

Phosphoinositide lipids (PIPs) play critical roles in development and the homeostasis of adult tissues and their dysfunction has been linked to major human diseases such as cancer, diabetes, myopathies and neuropathies.
  Kinase regulation of HOX transcription factors – a potential target in cancer?
  Research Group: Institute of Cancer Therapeutics
  Prof R Morgan, Dr S Shnyder
Applications accepted all year round

Funding Type

PhD Type

The HOX genes are a family of transcription factors that have a number of important functions in cancer, including cell survival and metastasis.
  Obtaining mechanistic insights into interplay of multiple effectors of oncogenic RAS molecules
  Dr K Tanaka, Dr A Revyakin
Application Deadline: 7 June 2020

Funding Type

PhD Type

The RAS family of small GTPases act as signalling hubs regulating cell proliferation and differentiation. Importantly, about 20% of all human cancers harbour mutations in RAS genes (COSMIC).
  Deep learning approaches to discover new roles for non-canonical protein modifications in cancer
  Prof C E Eyers, Prof A Jones
Applications accepted all year round

Funding Type

PhD Type

Abnormal protein phosphorylation is strongly associated with cancer aetiology. Considerable efforts have been undertaken to profile phosphorylation signalling networks acting through serine, threonine and tyrosine residues.
  Identifying inhibitors specific to the OPG-kinome: towards novel treatments for Pulmonary Arterial Hypertension (PAH).
  Prof A Lawrie, Dr R Thompson
Applications accepted all year round

Funding Type

PhD Type

Background. Pulmonary arterial hypertension (PAH) is a fatal progressive disease. Median life expectancy in untreated PAH patients is 2.8 years.
  Neuronal Src kinases: oncogenes in brain development?
  Dr G Evans, Dr S Chawla
Application Deadline: 30 June 2020

Funding Type

PhD Type

The challenges of the developing human brain include co-ordinating the birth and migration of 100 billion neurons and the formation of their 1000 trillion synaptic connections.
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