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We have 42 kinase PhD Projects, Programmes & Scholarships

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kinase PhD Projects, Programmes & Scholarships

We have 42 kinase PhD Projects, Programmes & Scholarships

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Using chemical-genetics to inhibit and characterise “undruggable” enzymes

University of Dundee School of Medicine
The ability to inhibit kinases with small molecule drugs has transformed our understanding of signalling networks. It has allowed us to define the substrates and processes that each kinase controls, and to map how these enzymes cooperate within signalling pathways. Read more
 Supervisors: Dr A Saurin, Dr T Ly
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Biophysical explorations of neural crest cell behaviours in development and cancer

King’s College London School of Natural & Mathematical Sciences
Neural crest cells are highly migratory. These cells travel throughout the developing embryo, eventually contributing to most organ systems, including the peripheral nervous system, pigment cells and craniofacial skeleton. Read more
 Supervisors: Prof R Isaacson, Prof K Liu
 10 May 2024  PhD Research Project  Funded PhD Project (Students Worldwide)
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Unravelling the mechanisms behind plant stress sensing

University of Oxford Department of Biology
Agricultural production and food security are severely threatened by the loss of arable land and climate change, with increasingly harsher droughts, floods, and heat waves reducing crop productivity by more than 50%. Read more
 Supervisors: Dr J Bolla, Dr EBG Baena-Gonzalez
 Year round applications  PhD Research Project  Funded PhD Project (UK Students Only)
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MSc by Research: Regulation of Kinetochore function by PLK1

University of Dundee School of Life Sciences
Accurate partition of the duplicated genome during cell division is crucial for cellular viability and organismal development. Chromosome mis-segregation is a major source of aneuploidy and it is a hallmark of cancer, while in oocytes represents the major source of miscarriages and genetic disease. Read more
 Supervisor: Dr F G Pelisch
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Molecular level understanding of Mycobacterium tuberculosis

University of Leicester Department of Respiratory Sciences
Mycobacterium tuberculosis has evolved to survive and replicate inside macrophages. The project will investigate the molecular mechanisms underpinning adaptation to this specialised intracellular niche. Read more
 Supervisors: Dr H O'Hare, Dr N Garton
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Molecular Glues as Novel Tools for Tackling Big Challenges in Human Health

University of Leicester Department of Chemistry
Background. The need for new medicines is greater than ever because of an ageing population and the complex clinical challenges brought about by drug resistance and/or side effects. Read more
 Supervisors: Dr RD Doveston, Prof S Macip
 23 May 2024  PhD Research Project  Competition Funded PhD Project (UK Students Only)
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Live cell imaging of epithelial cancer cell proliferation for therapy

University of Leeds Faculty of Biological Sciences
The School of Molecular & Cellular Biology invites applications from prospective postgraduate researchers who wish to commence study for a PhD in the academic year 2024/25. Read more
 Supervisors: Prof A Divan, Dr S Ponnambalam, Dr M A Harrison
 Open Day(s)  Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Lessening Health Inequalities in Type 2 Diabetes Through Innovative Drug Repurposing

University of Dundee School of Medicine
Most older type 2 diabetes (T2D) drugs were developed through pre-clinical studies and then trials that model T2D as it is experienced by older white people (1). Read more
 Supervisor: Prof G Rena
 30 June 2024  PhD Research Project  Self-Funded PhD Students Only
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Investigating the role of neutrophil-mediated tissue damage in a model of lupus nephritis

University of Liverpool Institute of Life Course and Medical Sciences
Systemic lupus erythematosus (SLE) is a rare autoimmune disease that affects around 5 million people worldwide. It disproportionately affects women and is incurable. Read more
 Supervisors: Dr HL Wright, Dr D Wilkinson, Dr D Turner
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Exploring the roles of dynamic atypical protein phosphorylation in cancer

University of Liverpool Institute of Systems, Molecular and Integrative Biology
Proteins are extensively regulated by dynamic, often reversible post-translational modifications (PTMs). This process allows cells to respond rapidly to environmental factors, be that e.g. Read more
 Supervisors: Prof C E Eyers, Prof A Jones
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Treating Glioblastoma: Tricyclic antidepressants repositioned and administered as a cancer therapy by a novel nanoparticle delivery system in vitro

Kingston University Faculty of Health, Science, Social Care and Education
Cancer is a disease that is rapidly increasing. The initiation and progression of cancer is a central topic of countless research with discoveries of multiple pathways implicated in formation and advancement of this debilitating disease. Read more
 Supervisor: Dr A Elbediwy
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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Analysing the role of statins in cardiovascular protection

University of Liverpool Department of Pharmacology and Therapeutics
Drug-induced cardiovascular toxicity is a major problem affecting a number of cancer chemotherapy drugs (Cross et al., 2015). Read more
 Supervisors: Dr M Cross, Dr B Wilm, Dr AM Mondru
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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ERK5 MAPK signalling in Alzheimer’s disease

University of Bradford Faculty of Life Sciences
  Research Group: Pharmacology and Experimental Therapeutics
Neurodegenerative diseases have devastating effects on individuals’ lives and our society, with no effective treatments available. Read more
 Supervisors: Dr J Muller, Dr S Kantamneni
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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The role of extracellular vesicles in lung epithelial cell communication in health and disease

University of Salford School of Science, Engineering and Environment
There is an opportunity to apply for a widening participation scholarship (available to UK candidates or those eligible for UK fees) can be found here. Read more
 Supervisor: Dr P Miklavc
 Year round applications  PhD Research Project  Self-Funded PhD Students Only
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Biological significance, predictive value and targeting of cell surface antigens in colorectal cancer

Kingston University Faculty of Health, Science, Social Care and Education
Despite major advances in its early detection, preventive measures and therapeutic options, colorectal cancer remains one of the most commonly diagnosed cancer and a leading cause of cancer deaths worldwide. Read more
 Supervisor: Dr S. K Khelwatty
 Year round applications  PhD Research Project  Competition Funded PhD Project (Students Worldwide)
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