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leukaemia PhD Projects, Programs & Scholarships

We have 15 leukaemia PhD Projects, Programs & Scholarships

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  Defining the ‘molecular signature’ of PARP inhibitor sensitivity in blood cancers
Kingston University Faculty of Science, Engineering and Computing
  Dr T Gaymes
Applications accepted all year round
Despite significant advances in the understanding of the biology of blood cancers, identification of the most effective and safe form of treatment continues to present a formidable challenge to clinicians.
Details
Type/Funding
  Exploring mechanisms underlying fibroblast mediated chemotherapy resistance in acute myeloid leukaemia – School of Health & Life Sciences
Glasgow Caledonian University School of Health and Life Sciences
  Dr M Williams, Dr C Bartholomew, Dr H Wheadon
Application Deadline: 14 April 2019
Background.
Details
Type/Funding
  Development of targeted therapy for acute myeloid leukaemia with mutations in isocitrate dehysdrogenase
Peter MacCallum Cancer Centre Sir Peter MacCallum Department of Oncology, University of Melbourne
  Dr L. Kats
Applications accepted all year round
Acute Myeloid Leukaemia (AML) is an aggressive disease with poor prognosis and development of novel treatment options is urgently needed.
Details
Type/Funding
  Understanding the role of the Guanosine Trimethylase TGS1 in Acute myeloid leukaemia
University of Cambridge Department of Pathology
  Dr I Barbieri
Application Deadline: 31 March 2019
RNA methylation is a reversible post-translational modification to RNA that epigenetically numerous biological processes. The biological and molecular functions of RNA methylation are generally very poorly understood, both in normal and pathological biological processes.
Details
Type/Funding
  Epigenetics and Cancer: Development of Novel Tools to Determine how Aberrant V(D)J Recombination Reactions Cause Leukaemia
University of Leeds Faculty of Biological Sciences
  Dr J Boyes
Applications accepted all year round
V(D)J recombination generates a highly diverse set of immunoglobulin and T cell receptor genes to enable vertebrates to fight a vast range of infections.
Details
Type/Funding
  Role of BTG1 and BTG2 in acute lymphocytic leukaemia and diffuse large B-cell lymphoma
University of Nottingham School of Pharmacy
  Dr G S Winkler
Applications accepted all year round
Acute lymphocytic leukaemia (ALL) and diffuse large B-cell lymphoma (DLBCL) is often associated with small deletions of or point mutations in the highly related BTG1 or BTG2 genes.
Details
Type/Funding
  Normal and Leukaemic Haemopoiesis: Understanding the fundamental biological processes underlying normal and malignant haematopoiesis and translate this to improve patient outcomes through new rational therapies.
University of Oxford Radcliffe Department of Medicine
  Dr P Vyas, Prof Claus Nerlov, Prof I Roberts
Application Deadline: 26 July 2019
Understanding the fundamental biological processes underlying normal and malignant haematopoiesis and translate this to improve patient outcomes through new rational therapies.
Details
Type/Funding
  Structure based design of novel warheads for use in peptide-drug conjugates
University of Manchester Faculty of Biology, Medicine and Health
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
Details
Type/Funding
  Molecular pathogenesis of the myelodysplastic syndromes: investigation of the molecular mechanisms involved in disease initiation and progression in the myeloid malignancy myelodysplastic syndromes (MDS)
University of Oxford Radcliffe Department of Medicine
  Dr J Boultwood, Dr A Pellagatti
Application Deadline: 26 July 2019
The main focus of our group is the investigation of the molecular mechanisms involved in disease initiation and progression in the myeloid malignancy myelodysplastic syndromes (MDS).
Details
Type/Funding
  Transcriptional programming of chromatin in normal and malignant haematopoiesis
University of Birmingham Institute of Cancer and Genomic Sciences
  Prof C Bonifer
Applications accepted all year round
In our work, we address the question of how the regulators of transcription, the sequence-specific DNA binding proteins or transcription factors, interact with the chromatin template and change its structure.
Details
Type/Funding
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