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lipid PhD Projects, Programmes & Scholarships

We have 97 lipid PhD Projects, Programmes & Scholarships

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We have 97 lipid PhD Projects, Programmes & Scholarships

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Early events in formation of the Immunological Synapse: Role of lipid microdomains in protein recruitment and sorting

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
Background. The immunological synapse is a specialised cell-cell junction between an antigen presenting cell and a lymphocyte (T-cell) composed of >20 immune receptors that function in a concerted manner (Fig.1A). Read more

Understanding by creating – minimal systems to reveal the underlying mechanisms governing the cell membrane shape and function

  Research Group: Midlands Integrative Biosciences Training Partnership (MIBTP)
The cell plasma membrane is essential for communication between the cell and its environment. It is here that crucial information processing takes place – including steps of signal detection, integration, amplification and transmission. Read more

Deciphering the lipid code for lysosomal channels and transporters in inflammatory, metabolic, and neurological disorders

Brief description of project. The lysosome has emerged as a central signalling centre within the eukaryotic cell. A key role for membrane proteins in the lysosomal membrane has been identified, as signalling systems that recruit kinases to activate downstream signalling pathways. Read more

The cutaneous lipidome: Does ethnicity impact skin’s lipid barrier?

Historically, skin research has focused on the properties of white Northern European (or Caucasian) skin. Consequently, our knowledge of skin biology in individuals from different ethnicities is much less advanced. Read more

Safer, scalable, and modifiable polymer-based lipid nanocapsules for drug delivery

Lipid nanocapsules (LNCs) are very interesting nanoformulations as they can be made by phase inversion technique (PIT), a scalable method with predictable particle size at the beginning of the preparation process. Read more

Development of RNA-loaded lipid nanomedicines for therapeutic and vaccines applications

Project - Recent mRNA vaccine success has heralded a new era of RNA nanomedicines. A few challenges remain to realise the full potential of RNA nanomedicines for therapeutic or therapeutic vaccine applications, including translation efficiency, targeted delivery and stability. Read more

Understanding the skin barrier through molecular simulation

The barrier function of skin is known to be localized to the stratum corneum, the outermost layer of the skin. The stratum corneum is composed of corneocytes (dead skin cells) surrounded by a dense lipid matrix that serves as the only continuous path for permeation through the skin. Read more

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