Pancreatic cancer is one the most common causes of cancer death in the world. One characteristic of pancreatic cancer in humans is the presence of a dense fibrous stroma which may comprise up to 80% of the tumour mass.
Biopharmaceuticals have been increasingly used in the treatment of skin diseases. However, due to the poor absorption of peptide and protein through the skin, they are usually delivered through injections.
Cancer continues to impose a vast burden with regard to financial costs as well as human suffering but the progress in its treatment is hindered by the limited selectivity and significant side-effects that the current chemotherapy demonstrates, representing a major challenge for modern drug delivery.