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liver cancer PhD Projects, Programs & Scholarships

We have 20 liver cancer PhD Projects, Programs & Scholarships

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  Metabolic Reprogramming in Liver Cancer: delineating the role of reactive oxygen species (ROS) in tumour development
  Prof T. Tiganis
Applications accepted all year round

Funding Type

PhD Type

The Tiganis Laboratory is seeking a highly enthusiastic student to conduct research in cancer metabolism and obesity-associated liver cancer.
  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  Fishing for metabolic clues: Role of the Hippo/Yap pathway in reprogramming metabolism in liver cancer
  Dr A. Cox
Applications accepted all year round

Funding Type

PhD Type

The Hippo/Yap pathway is an evolutionarily conserved cascade that plays a fundamental role in governing organ size control, stem cell homeostasis and cancer.
  Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy
  Prof K Gaston, Dr P-S Jayaraman
Applications accepted all year round

Funding Type

PhD Type

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies.
  Exploiting stemness as a cancer cell vulnerability using hepatocellular carcinoma as a model system
  Dr S Ma
Applications accepted all year round

Funding Type

PhD Type

Tumors are composed of non-homogeneous cell populations exhibiting varying degrees of genetic and functional heterogeneity. Cancer stem cells (CSCs) are capable of sustaining tumors by manipulating genetic and non-genetic factors to metastasize, resist treatment, and maintain the tumor microenvironment.
  Centrosome Amplification and Cancer
  Dr Y Ching
Applications accepted all year round

Funding Type

PhD Type

Centrosome, which is the microtubule-organising center (MTOC) in the cell, plays a critical role in determining the motility, polarity and division of cell.
  Transglutaminase 2 (TG2) as a novel cancer biomarker and target for chemotherapy
  Research Group: Biomedical Research Group
  Dr P Coussons, Dr C Pike
Applications accepted all year round

Funding Type

PhD Type

Research Group. Biomedical Research Group. https://www.anglia.ac.uk/science-and-engineering/research/institutes-and-groups/biomedical.
  Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death
  Dr S Papa
Applications accepted all year round

Funding Type

PhD Type

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow.
  Chemotherapy dose-capping due to obesity and its impact on survival
  Prof A Renehan, Dr Jorge Barriuso
Applications accepted all year round

Funding Type

PhD Type

Obesity is associated with risk for several cancer types, including colorectal and breast cancers (1). Obesity also predicts for a poor outcome after cancer treatment.
  Bioinformatics for Personalized and Precision Neoantigen Therapeutics in Cancer
  Prof T Hupp, Dr JA Alfaro
Applications accepted all year round

Funding Type

PhD Type

Despite the success of immune checkpoint inhibitors in the clinic, most cancer patients do not respond, and even among responders therapeutic resistance is a problem.
  PhD in Chemistry – Luminescent arrays for the detection of liver disease
  Dr W Peveler
Application Deadline: 31 August 2020

Funding Type

PhD Type

This PhD project will seek to improve the speed, sensitivity and accuracy of a sensor array for detecting biomarkers of liver fibrosis, leading to a better blood test for the condition (https://doi.org/10.1002/adma.201800634).
  Precision Medicine DTP: Structural effects of cross-kingdom miRNA on regulation of RNA function in cancer
  Research Group: Edinburgh Cancer Research Centre
  Prof T Hupp, Dr A Rajan
Application Deadline: 1 June 2020

Funding Type

PhD Type

Scientific research in the 20th century has established that plant-derived dietary vitamins and minerals can have a positive impact on human health.
  Defining the microbiome environment in patients with biliary tract cancer and its implications for therapy
  Prof J W Valle, Dr M McNamara
Application Deadline: 30 November 2020

Funding Type

PhD Type

Biliary tract cancers (BTCs) encompass cancers of the extrahepatic/intrahepatic bile ducts, gallbladder and ampullary carcinoma. The only potentially curative option is surgical resection; median overall survival (OS) in the advanced setting.
  Development of “FXR-targeted” Nutraceuticals for Treatment of Intestinal Diseases
  Prof S Keely, Dr S Das
Applications accepted all year round

Funding Type

PhD Type

The incidence of intestinal diseases, such as colorectal cancer (CRC) and inflammatory bowel disease (IBD), is significantly higher in Western societies than elsewhere in the world.
  Exploring new strategies for the inhibition of bile duct cancer (Cholangiocarcinoma)
  Dr P-S Jayaraman, Prof K Gaston
Applications accepted all year round

Funding Type

PhD Type

Cholangiocarcinoma (CCA) arises from the transformation of cholangiocytes of the epithelial bile duct/ductules within the liver. The incidence and mortality rates for CCA are increasing worldwide and a better understanding of how CCA develops and new treatment options are urgently needed.
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