We have 20 liver cancer PhD Projects, Programmes & Scholarships

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liver cancer PhD Projects, Programmes & Scholarships

We have 20 liver cancer PhD Projects, Programmes & Scholarships

Investigating the communication between cancer cells and cells in the tumour microenvironment to improve our understanding of epigenetic regulatory mechanisms and identify new targets for cancer therapy

It is well-established that the molecular mechanisms controlling gene expression are disrupted in cancer cells and work in this area has laid the foundations for targeted cancer therapies. We are interested in the regulatory pathways that control cell proliferation and cell migration and the events that disrupt this control in multiple types of cancer. Read more
Last chance to apply

Unravelling NAFLD-Driven Cardiovascular Dysfunction: Insights from iPSC-Derived Cardiomyocytes and Hepatocytes

Liver disease accounts for 3.5% of all global deaths/year (~2 million people) and is the third leading cause of premature death in the UK with some of the highest hospitalisations in the country seen in areas of socioeconomic deprivation. Read more

Metabolic reprogramming in cancer: starving tumors of essential nutrients to promote cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Cancer: Inhibiting cell metabolism to enhance tumour cell death

All the cells in our bodies are programmed to die. As they get older, our cells accumulate toxic molecules that make them sick. In response, they eventually break down and die, clearing the way for new, healthy cells to grow. Read more

Analysis of the role of liver sinusoidal endothelial cells in methotrexate-induced liver toxicity

Liver sinusoidal endothelial cells (LSECs) comprise approximately 50% of the non-parenchymal hepatic cells. They play a vital role in hepatic microcirculation and provide a physiological barrier to the movement of xenobiotics from the bloodstream to hepatic tissue. Read more
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Advancing clinical elastography for early, non-invasive imaging assessment of normal tissue toxicity and tumour response

This PhD project offers an opportunity for an experimental scientist to work as part of a multi-disciplinary team to develop MR-Elastography and US-Elastography for the benefit of patients with cancer. Read more

Collagen and the tumour microenvironment

 Collagen is the most abundant protein in the human body, and has an important role in connective tissues. However, when found in the tumour microenvironment it is often linked to a poor prognosis, for example in breast and pancreatic cancer. Read more

Development of deep learning methods and software to infer pathway enrichment from histology images - application to liver fibrosis

Histopathological images are routinely used to characterize complex phenotypes. For example, pathologists regularly study stained images of tissue biopsies for cancer diagnosis as cancer is known to change the morphological features of cells including cell shape and size [1]. Read more

Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

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