We have 32 lung cancer PhD Projects, Programmes & Scholarships

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lung cancer PhD Projects, Programmes & Scholarships

We have 32 lung cancer PhD Projects, Programmes & Scholarships

Cancer biology: identification of new treatment options for EML4-ALK driven lung cancer through understanding mechanisms of cell division and migration.

Lung cancer is the largest cause of cancer-related deaths in the UK and worldwide. While little progress has been made in long-term survival rates, we now have a good understanding of the genetic drivers raising the prospect of earlier diagnosis and more effective treatments. Read more

Studying lymph node stroma-immune interactions in lung cancer to improve immunotherapy

We are seeking to appoint a PhD research student to join the translational tumour immunology group led by Dr Alan G. Ramsay and Dr Anthony Kong, as part of an industrial collaboration with Dr Rachel Evans, AstraZeneca (Industrial CASE, iCASE studentship). Read more

Driving phenotypic plasticity and metastasis in small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive malignancy with poor prognosis. Underlying this aggressiveness is intra-tumoural heterogeneity driven by phenotypic plasticity wherein tumour cells transition from a neuroendocrine (NE) to a non-neuroendocrine (non-NE) phenotype. Read more

(MRC DTP) Investigating the link between nuclear deformation and lung cancer migration and invasion

Migration and invasion are essential features of malignant cells that underlie metastatic potential. Controlling nuclear size, shape, orientation, and position along a cell’s front-rear axis is crucial for optimal directional migration and invasion. Read more

Repurposing and enriching cardiovascular risk prediction model to identify people at risk of cancer – UCL (part of Health Data Research UK’s Big Data for Complex Disease Driver Programme)

Risk-stratified management of cardiovascular disease (CVD), where people without established disease receive preventative interventions and monitoring based on their 10-years predicted risk, has been highly successful to ensure healthcare resources are allocated to those most likely to benefit. Read more

Inducing ferroptotic death to kill cancer cells

Ferroptosis is an iron-dependent form of regulated necrotic cell death triggered by oxidative degradation of lipids in membrane bilayers and subsequent irreparable damages to the plasma membrane (1). Read more

Computational and machine learning driven development of new polysialyltransferase (ST8SiaII) inhibitors against metastatic cancer

  Research Group: Institute of Cancer Therapeutics
Polysialic acid (polySia) is a carbohydrate polymer important for embryonic development. PolySia is absent in healthy adult tissues whereas overexpressed in several tumours. Read more

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