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macrophage PhD Projects, Programmes & Scholarships

We have 13 macrophage PhD Projects, Programmes & Scholarships

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We have 13 macrophage PhD Projects, Programmes & Scholarships

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Macrophage driven therapy resistance in AML: from macrophage subset characterisation to therapeutic targeting.

  Research Group: Molecular Mechanisms and Long Term Conditions
Reference. SHLS20065. Background. Acute Myeloid Leukaemia (AML) is a common blood cancer in adults; with its incidence increasing with age, AML cases are predicted to double by 2030. Read more

4-year PhD Studentship: Elucidating the inflammatory crosstalk between Coronary Artery Disease and Alzheimer's Disease

There is now substantial data demonstrating an association between high morbidity and mortality cardiovascular diseases (such as atherosclerosis and atherosclerotic aneurysms) with the onset of neurodegenerative diseases, particularly those characterised by neuroinflammation such as Alzheimer's Disease. Read more

Helminth products as macrophage “trainers”: a novel therapeutic tool for the treatment of immune mediated diseases

The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more

Helminth products as macrophage “trainers”: a novel therapeutic tool for the treatment of immune mediated diseases

The innate immune system can display characteristics of immunological memory. This phenomenon, termed “trained immunity”, refers to the long-term functional reprogramming of innate immune cells after the encounter with infectious or non-infectious agents that influences their capacity to respond to a secondary stimulus. Read more

Using microfluidics and flow cytometry to develop novel diagnostics for Leishmaniasis

The Leishmaniases are a group of neglected tropical diseases caused by >20 species of Leishmania parasites that are spread by >90 species of phlebotomine sand flies. 1 billion people in Africa, Asia, the Americas and the Mediterranean are at risk, with the poor and malnourished being disproportionately affected. Read more

Novel anti-pathogen regulatory mechanisms driven by Human Guanylate Binding Proteins

Human GBPs are a family of seven ~65kDa GTPases whose expression is upregulated by IFNg, for example during an infection. All mammalian GBPs contain a GTPase domain and a C-terminal helical region. Read more
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