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We have 32 mammalian cell culture PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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mammalian cell culture PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 32 mammalian cell culture PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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How do mammalian cells handle mRNA therapeutics: Optimising the molecular basis of manufacture

The use of mRNA to generate vaccines against COVID-19 has cemented the potential for nucleic acids to develop approaches to prevent viral infection and to have wider applications in the treatment of life-threatening cancers (Nature [2021] 589. Read more

Cancer: Epigenetic therapy using microbubble-mediated drug delivery for colorectal cancer

The project is an interdisciplinary, pre-clinical study that aims to investigate the response of human tumour cells to treatment with epigenetic inhibitors (including DNA methyltransferase inhibitors, HDAC inhibitors and/or vitamin C), as a potential combination therapy for colorectal cancer (CRC). Read more

Chemical glycoengineering of therapeutic antibodies

Glycosylation is the most common posttranslational protein modification. Recombinant therapeutic glycoproteins (RTGs) such as monoclonal antibodies (mAbs) are decorated with complex glycans that determine not only their efficacy but also other critical parameters such as in vivo half-life, stability and antigenicity. Read more

Meals for macrophages – investigating how macrophages engulf and process dying cells in vivo

Supervisors. Iwan Evans (primary supervisor); Phil Elks and Simon Johnston (secondary supervisors). Project details. A critical role for phagocytic cells such as macrophages is the engulfment and subsequent degradation of dying cells and debris. Read more

EPSRC CDT in Bioprocess Engineering Leadership: Complex Biological Products Manufacture

Biological products and their manufacture are progressing to unparalleled levels of complexity. Examples include engineered biocatalysts, antibody-drug conjugates, multivalent vaccines and cellular therapies. Read more
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Executive Dean’s PhD Studentship in the Development of a cellular model of rob(15;21) translocation for acute lymphoblastic leukaemia.

About the Project. The team of Prof Vagnarelli, Dr Tosi and Prof Sala at Brunel University London is offering a fully funded PhD studentship to develop a cellular model of Robertsonian chromosome translocation (15;21) to study the evolution of acute lymphoblastic leukaemia (ALL). Read more

To investigate the role of molecular regulators in the control of scarring and wounding tissue

Skin morphogenesis occurs under stringent control of epithelial-mesenchymal interactions and result in a formation of the epidermis and a number of different skin appendages (including, the hair follicle, HF). Read more

Investigating the Mitotoxicity of Fluoroquinolone Antibiotics

Applications are invited for a self-funded, 3 year full-time or 6 year part-time PhD project. The PhD will be based in the School of Pharmacy and Biomedical Science and will be supervised by Dr Robert Baldock. Read more

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