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manchester PhD Projects, Programmes & Scholarships

We have 445 manchester PhD Projects, Programmes & Scholarships

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We have 445 manchester PhD Projects, Programmes & Scholarships

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(EPSRC DTP) Mapping SUMO interactions in DNA repair using EPR, NMR and molecular modelling

Understanding the process by which DNA double-strand breaks are repaired via non-homologous end joining (NHEJ) is vital for the design and precision of future anti-cancer medicines and the optimisation of CRISPR/Cas9-based gene editing. Read more

Mapping ancient biomolecule degradation through omics methods

The University of Manchester faculty of Biology, Medicine and Health (. https://www.bmh.manchester.ac.uk/. ) is offering a unique self-funded PhD studentship in mapping ancient biomolecule degradation using omics techniques. The KNH Centre of Biomedical Egyptology at the University of Manchester (. Read more

Method development and applications of Electron Paramagnetic Resonance (EPR)

Electron Paramagnetic Resonance (EPR) is a spectroscopic tool used to study systems containing unpaired electrons. EPR has wide ranging applications from materials science and quantum computing to structural biology and (bio)catalysis. Read more

The acquisition of complex sentences in children

Complex sentences such as those involving adverbial clauses (Before you eat your dinner, wash your hands) appear in children’s speech at about three years of age yet experimental studies have found that children have difficulty comprehending these sentences well into the school years. Read more

Proteomics to determine how defects in membrane trafficking within the secretory pathway cause human disease

Work in the Lowe laboratory is aimed at deciphering the molecular mechanisms that control membrane trafficking within cells. A major focus of our work is the trafficking of proteins to and through the Golgi apparatus, which lies at the heart of the secretory pathway. Read more

Understanding disease mechanisms in autoimmune inflammatory muscle disease

The idiopathic inflammatory myopathies are a spectrum of rare autoimmune disorders characterized by inflammation of muscle tissue (myositis), which leads to muscle weakness and fatigue, and heterogeneous systemic organ involvement. Read more

Understanding apoptotic heterogeneity in cell populations

Apoptosis is a form of programmed cell death that occurs in response to stress such as genomic damage. The decision to initiate apoptosis is taken at the outer mitochondrial membrane (OMM) by members of the Bcl-2 family of proteins. Read more

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