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mechanism PhD Projects, Programs & Scholarships

We have 429 mechanism PhD Projects, Programs & Scholarships

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  MRC DiMeN Doctoral Training Partnership: Genomic translocations, super-enhancer hijacking and oncogene activation: from mechanism to therapy
Newcastle University MRC DiMeN Doctoral Training Partnership
  Dr L Russell, Dr D Rico, Prof S Hambleton, Dr A Corcoran
Application Deadline: 21 January 2019
Background. Haematopoiesis is a developmental process which culminates in the formation of all the blood cells required in our immune system.
Details
Type/Funding
  Termination of DNA replication: mechanism and importance
University of Birmingham Institute of Cancer and Genomic Sciences
  Dr A Gambus, Dr M Saponaro
Application Deadline: 6 January 2019
Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA replication must be precisely regulated as unrepaired mistakes can change cell behaviour with potentially severe consequences, such as genetic disease, cancer and premature ageing.
Details
Type/Funding
  Understanding the mechanism of action of ferro-nucleobase analogues
University of Birmingham School of Biosciences
  Dr N J Hodges
Applications accepted all year round
Through collaboration with Professor Jim Tucker (School of Chemistry) we are studying the cellular effects of a novel DNA base analogues based on the organometallic compound ferrocene.
Details
Type/Funding
  Using advanced MD simulation for understanding biomolecular mechanism (HAYWARDSU19SF)
University of East Anglia School of Computing Sciences
  Dr S Hayward
Application Deadline: 31 May 2019
Many biomolecules act as molecular machines and have a precise mechanism. Understanding how biomolecules work in detail could bring great advances in medicine and other biotechnologies.
Details
Type/Funding
  MRC DiMeN Doctoral Training Partnership: Discovering the neuronal signalling mechanism at the heart of cardiac arrhythmias
University of Leeds MRC DiMeN Doctoral Training Partnership
  Dr I Jayasinghe, Prof N Gamper, Prof E White
Application Deadline: 21 January 2019
Background. Cardiac arrhythmias are a leading cause of mortality and long-term morbidity worldwide. Over 25% of these originate in the heart’s electrically-autonomous (pacemaking) cells without a detectable heart attack.
Details
Type/Funding
  (BBSRC DTP) Structure and functional study to probe the mechanism of BMP regulation by the chordin family
University of Manchester Faculty of Biology, Medicine and Health
  Prof C Baldock, Prof H Ashe, Dr A Roseman
Application Deadline: 31 January 2019
Bone morphogenetic proteins (BMPs) are key signalling molecules in embryonic development and adult tissue homeostasis, and are heavily regulated in the extracellular matrix.
Details
Type/Funding
  PhD Studentship in Cell and Molecular Biosciences - Elucidating the assembly mechanism of the Tat protein export machinery
Newcastle University Institute for Cell and Molecular Biosciences
  Prof T Palmer
Application Deadline: 31 January 2019
Number of awards. 1. Start date and duration. 23 September 2019 for 3 years. Overview. The twin arginine protein transport (Tat) system is a conserved and highly unusual protein transport pathway that exports folded proteins across the cytoplasmic membranes of bacteria.
Details
Type/Funding
  PhD position in Developmental Neurobiology: to understand the role and mechanism of action of the Prdm12 gene
Université libre de Bruxelles (ULB) & Université de Mons (UMONS) Neuroscience Institute
  Dr E Bellefroid, Dr A Garcia-Pino
Application Deadline: 31 March 2019
We are seeking highly motivated candidates to join us on a project beginning in 2019 on the molecular mechanisms of sensory neurogenesis.
Details
Type/Funding
  Elucidating the mechanism of SMC complexes
University of Bristol School of Biochemistry
  Prof M Dillingham
Applications accepted all year round
The segregation of bacterial chromosomes is orchestrated by the co-ordinated actions of ParB and condensin [1]. ParB (also called Spo0J) is a site-specific DNA binding protein that binds at and around parS sequences near the origin of replication to form “ParB networks” which define the bacterial centromere [2].
Details
Type/Funding
  Mechanism of transmembrane receptor activation
University of Cambridge Department of Biochemistry
  Dr M Hyvonen
Applications accepted all year round
Applications are invited for a PhD position, starting in October 2019, in the group Dr Marko Hyvonen at University of Cambridge (http://hyvonen.bioc.cam.ac.uk/) to study the mechanism of transmembrane signalling by TGFbeta family growth factors.
Details
Type/Funding
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