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medicinal chemistry PhD Projects, Programs & Scholarships

We have 33 medicinal chemistry PhD Projects, Programs & Scholarships

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  Biomolecular Science and Medicinal Chemistry Division PhD project: Proteases in the ubiquitin system – from molecular mechanisms to the development of novel inhibitors
University of Nottingham School of Pharmacy
  Dr I Dreveny
Applications accepted all year round
Ubiquitin is a posttranslational modifier that tags substrate proteins for degradation and regulates virtually all known cellular processes.
Details
Type/Funding
  Synthetic Medicinal Carbohydrate Chemistry PhD in the area of Glycomimetics.
National University of Ireland, Galway Department of Chemistry
  Dr P Murphy
Application Deadline: 1 April 2019
The successful candidate will work on a project concerned with the design and synthesis of glycomimetics. Specifically they will synthesize complex target molecules designed against various targets such as galectin-8 and siglec-8 involved in asthma and some forms of inflammation/cancer.
Details
Type/Funding
  Exploiting druggability host spots in protein phosphatase targets
University of Manchester Faculty of Biology, Medicine and Health
  Dr L Tabernero, Prof D Procter, Dr S Butterworth
Applications accepted all year round
In the past years the use of virtual screening or computer-based screening of compound libraries against selected targets has expanded exponentially the boundaries of drug discovery.
Details
Type/Funding
  Development of new serine protease inhibitors by optimisation of rationally designed covalent S1 fragments
University of Nottingham School of Pharmacy
  Dr M Stocks, Dr J Emsley
Applications accepted all year round
The PhD studentship is an EPSRC Doctoral Training Partnership (https://epsrc.ukri.org/skills/students/dta/termsconds/) in collaboration with KalVista Pharmaceuticals a pharmaceutical company focused on the discovery, development, and commercialisation of small molecule protease inhibitors for diseases with significant unmet medical need.
Details
Type/Funding
  Structure based design of novel warheads for use in peptide-drug conjugates
University of Manchester Faculty of Biology, Medicine and Health
  Dr S Butterworth, Dr A Tirella, Dr D Wiseman
Applications accepted all year round
Chronic Myelomonocytic Leukaemia (CMML) is an orphan disease defined by myeloid dysplasia, myeloproliferation and a malignant expansion of classical monocytes.
Details
Type/Funding
  Synthetic Organic Approaches for Covalent Inhibition of Protein-Protein
University of Southampton Faculty of Engineering and Physical Sciences
  Dr S Thompson
Applications accepted all year round
We are looking for an enthusiastic and well-organized student with an interest in applying the full range of synthetic organic chemistry methods to design and construct conformationally well-defined molecules (foldamers) that covalently recognise key elements of protein surfaces.
Details
Type/Funding
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships
Durham University
Applications are invited from suitably qualified graduates for fully funded 4-year PhD studentships in the area of Molecular Sciences for Medicine (MosMed) and will focus on unmet medical needs.
Details
Type/Funding
  EPSRC Centre for Doctoral Training in Molecular Sciences for Medicine - 4 year PhD Studentships
Newcastle University Faculty of Science, Agriculture and Engineering
Applications are invited from suitably qualified graduates for fully funded 4-year PhD studentships in the area of Molecular Sciences for Medicine (MosMed) and will focus on unmet medical needs.
Details
Type/Funding
  PhD Studentship in MosMed CDT: Development of MRI scan methods to image inhaled fluorocarbon gases as biomarkers of lung structure and function
Newcastle University Institute of Cellular Medicine
  Dr P Thelwall
Application Deadline: 12 April 2019
Number of awards. 1. Start date and duration. September 2019 for 4 years. Overview. Lung diseases are a leading cause of death, and new treatments are emerging.
Details
Type/Funding
  Precious metals in the fight against cancer
University of Birmingham School of Pharmacy
  Dr I Romero-Canelon
Applications accepted all year round
Platinum-based complexes, Cisplatin, Oxaliplatin and Carboplatin, are the most widely used chemotherapeutics, nonetheless there is a major unmet clinical need for new treatments that expand the range of treatable cancers and overcome inherent and acquired platinum resistance.
Details
Type/Funding
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