We have 52 medicinal chemistry PhD Projects, Programmes & Scholarships

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medicinal chemistry PhD Projects, Programmes & Scholarships

We have 52 medicinal chemistry PhD Projects, Programmes & Scholarships

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Modular Synthetic Platform for the Optimisation of Fragment Hits to 3-D Lead Compounds for Medicinal Chemistry

Background. Fragment-based methods are established for the identification of lead compounds in drug discovery.[1] Fragments are small molecules (molecular weight ~150-300) which bind weakly to proteins. Read more

PhD in Chemistry: Medicinal Chemistry of Nucleotide Analogues

Nucleoside analogues (NAs) are an important class of antiviral and anticancer agents commonly used in the therapy of many different viral infections and cancer conditions. Read more

Broadening the spectrum of antibacterial drugs to tackle multi-drug resistant Gram-negative pathogens

  Research Group: Astbury Centre for Structural Molecular Biology
Antibiotics make possible the treatment and cure of life-threatening bacterial infections and have added over a decade to average human lifespan. Read more

Synthesis of macrocycles and medium-sized rings via new ring expansion approaches

Summary. Macrocycles (12+ membered rings) and medium-sized rings (8–11-membered) are cyclic molecules with great potential in many scientific fields and technologies – especially in medicinal chemistry. Read more

Towards New Antivirals for the Treatment of COVID-19: Fragment-Based Lead Generation of Small Molecule Inhibitors of the Nsp3 Macrodomain in SARS-CoV-2

Background. Coronaviruses (CoVs) are important human pathogens and SARS-CoV-2 is responsible for the COVID-19 pandemic. Notwithstanding progress in available vaccines for COVID-19, there remains a need to develop small molecule drug candidates for treating COVID-19. Read more

Design and synthesis of chemical tools to interrogate cannabinoid receptors

Research project. We are seeking a highly motivated PhD candidate to join an interdisciplinary team at the University of Otago, to undertake research developing chemical probes for the cannabinoid receptor, a type of G protein-coupled receptor (GPCR). Read more

Boron in drug and chemical probe discovery

We are seeking strongly motivated and competitive candidates to conduct PhD research as part of an internationally-recognised research team involved in drug discovery and chemical probe design based on the element boron. Read more

Faculty of Pharmacy, Masaryk University

Discover the art of developing life-changing pharmaceuticals through our Medicinal Chemistry program. The aim of this programme is to prepare qualified experts who will work professionally in scientific activities in the field of development and analysis of drugs and its application to other scientific fields. Read more

Investigation of the critical roles of platelets at the interface between thrombosis and inflammation in order to develop improved therapeutic strategies for the treatment and/or prevention of cardiovascular/inflammatory diseases

Platelets (small circulating blood cells) are involved in blood clotting to prevent excessive bleeding, however, their inappropriate activation under pathological conditions leads to thrombosis resulting in major cardiovascular diseases such as heart attack and stroke. Read more

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