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We have 9 melanoma PhD Projects, Programmes & Scholarships

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melanoma PhD Projects, Programmes & Scholarships

We have 9 melanoma PhD Projects, Programmes & Scholarships

The role of vitamin D3 in treating skin cancer and preventing drug resistance

  Research Group: Chemistry and Biosciences
During the last decade numerous studies have alluded to vitamin D. 3. playing a role in the prevention of cancer. Recent clinical trials looking at the potential role of vitamin D. Read more

Understanding Hormone Regulation in Skin Cancer Development and Progression

Skin cancers, including melanoma and non-melanoma skin cancers, pose a significant global health burden. While the role of hormones in skin cancer development and progression remains an underexplored area, recent research has suggested potential links between hormonal regulation and skin cancer outcomes. Read more

Pan cancer Ex vivo immunotherapy screening in 3D models

Immunotherapies are a fast evolving therapeutic area in the treatment of many cancer types. Here at Sheffield we have been working on ex vivo drug screening as part of the EVIDENT trial (NCT05231655). Read more

GAIA: Generating Artificial Intelligence Assisted Assessment for Alopecia

ADVERT. The impact of alopecia is highlighted in the Global Burden of Disease estimates of years lost to disability, where alopecia areata (AA) was ranked higher than both psoriasis and melanoma in disease impact. Read more

B cell responses during tumour development

The body remains free of infections and disease due to the cascade of actions of the cells and organs of our immune system. During tumour development, tumours induce changes within the local environment and in downstream locations, such as the lymph nodes. Read more

Cancer: Understanding the immunosuppressive role of fibroblast and macrophages in Breast cancer

Oncolytic viruses (OVs) preferentially infect and kill cancer cells, and their clinical efficacy has been demonstrated against a number of different cancers. The most clinically advanced OV is a genetically engineered herpes simplex virus (T-VEC) which expresses GMCSF to aid the development of anti-tumour immune responses; T-VEC is approved for the treatment of metastatic melanoma. Read more

Immunotherapy: Killing Cancer using Dead Virus

It is now accepted that our immune systems can hold the key to treating otherwise incurable cancers. So-called “immunotherapy” is an increasingly common method of treating tumours, leading to impressive increases in patient responses. . Read more

Cancer: Repurposing drugs as new treatments for breast cancer

Breast cancer (BC) is the most common cancer, with over 1 million new cases diagnosed worldwide each year. For some types of BC, hormonal treatments have been very effective but one particular BC subtype, triple negative breast cancer (TNBC), is highly aggressive and lacks a targeted therapy. Read more
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