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membrane PhD Projects, Programs & Scholarships

We have 138 membrane PhD Projects, Programs & Scholarships

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  The mechanism, function, and medically-relevant dysfunction of mitochondrial complex I (NADH:ubiquinone oxidoreductase) (On the University’s application portal, please select "PhD in Medical Science at the MRC Mitochondrial Biology Unit").
  Prof J Hirst
Application Deadline: 30 June 2020

Funding Type

PhD Type

Complex I (NADH:ubiquinone oxidoreductase) catalyses the first step in the respiratory chain and oxidative phosphorylation. NADH oxidation and quinone reduction, coupled to proton translocation across the inner membrane.
  Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy
  Dr J Bruce, Prof K Williams, Dr A P Gilmore
Applications accepted all year round

Funding Type

PhD Type

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy.
  Mapping the circadian clock-dependent regulation of the secretory pathway
  Prof K E Kadler, Dr Q-J Meng
Applications accepted all year round

Funding Type

PhD Type

The protein secretory pathway in cells comprises a series of membranous compartments and transport vesicles that the cell uses to synthesise, post-translationally modify, and move proteins for delivery to the plasma membrane or for secretion to the extracellular matrix.
  Organelle sorting and interconnectivity
  Prof P Verkade
Applications accepted all year round

Funding Type

PhD Type

Following internalisation of receptor-bound ligands into early endosomes Epidermal Growth Factor (EGF) is internalised into multi-vesicular bodies and degraded.
  Life’s ups and downs: probing the conformational dynamics of DASS transporters, a protein family associated with age-related diseases and lifespan determination (MACMILLANU20DTP)
  Dr F MacMillan, Dr J Angulo
Application Deadline: 25 November 2019

Funding Type

PhD Type

We study the architecture and functional dynamics of membrane proteins, especially many medically relevant membrane transport systems.
  Red blood cells and phagocytosis: how the immune system sorts new cells from old. PhD in Mathematics (GW4 BioMed MRC DTP)
  Dr D Richards
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr David Richards, Department of Mathematics, Living Systems Institute, University of Exeter. Charlie Jeynes, Department of Mathematics, Living Systems Institute, University of Exeter.
  Molecular analysis of neutrophil extracellular traps (NETs) in rheumatoid arthritis
  Dr HL Wright, Prof RJ Moots
Applications accepted all year round

Funding Type

PhD Type

Neutrophil extracellular traps (NETs) kill pathogens via the release of chromatin and anti-microbial granule enzymes in an extracellular mesh or “net”.
  Mechanisms controlling organelle dynamics and quality control
  Prof P Carvalho
Application Deadline: 10 January 2020

Funding Type

PhD Type

Our lab is interested in membrane-bound organelles- how they form and acquire their distinctive proteome essential to carry their specialized functions.
  Bacterial iron uptake pathways as targets for the development of novel antimicrobials
  Dr M Thomas
Applications accepted all year round

Funding Type

PhD Type

Antimicrobial resistance is an ever increasing problem. Presently it is estimated to be responsible for 700,000 deaths p.a. and it is predicted that this figure will rise to 10 million by 2050.
  Search for new regulators of intracellular trafficking in plants
  Dr T Nodzynski, Dr M Zwiewka
Application Deadline: 31 October 2019

Funding Type

PhD Type

Plants are the organisms providing oxygen for the biosphere being the fundamental element of food chain, therefore, basic understanding of molecular mechanisms guiding their growth is essential.
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