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metabolism PhD Projects, Programs & Scholarships

We have 215 metabolism PhD Projects, Programs & Scholarships

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We have 215 metabolism PhD Projects, Programs & Scholarships

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Deciphering the role of white and brown adipocytes in metabolic disease

Our work focuses on understanding how obesity drives the development of type 2 diabetes and cardiovascular disease. Specifically, it aims to decipher molecular determinants of adipocyte number and distribution within the body; key factors of susceptibility to obesity-associated cardiometabolic diseases. Read more

Exploiting human gut microbiome in mucus to combat pathogens (JUGE_Q22MMB)

This PhD studentship provides an exciting opportunity for the successful candidate to investigate gut symbiont-pathogen interactions at the mucosal surface and acquire advanced skills in both in silico and in vivo approaches. . Read more

Tumour metabolic and immune landscape in spatial resolution: using engineered bacterial cancer therapy to enhance anti-tumour T cell responses

Bacterial cancer therapy (BCT) is a promising and versatile therapeutic for solid tumours. Salmonella enterica Typhimurium (STm) is the most well-studied among bacterial vectors due to advantages in ease of genetic modification, metabolic adaptation, and motility. Read more

How does the metabolic status of the plant regulate embryo development and seed viability?

This project will discover how carbohydrate availability regulates embryo development and seed viability in Arabidopsis. Seed growth depends on the interplay between developmental/genetic programmes and carbohydrate supply from the maternal plant. Read more

Evaluation of MCT1s role in chromatin remodelling and metabolomics changes involved in cancer progression

Monocarboxylate transporter 1 (MCT1) is a transmembrane protein involved in cell metabolism and mediates transport of monocarboxylates (such as pyruvate {a metabolic substrate} and lactate {a metabolic by product}) in and out of the cell. Read more

Cutting off the fuel supply to calcium pumps in pancreatic cancer: a novel therapeutic strategy

Background and Rationale. Pancreatic ductal adenocarcinoma (PDAC) has the poorest survival and limited treatment options. Therefore, the search for novel therapeutic targets and drugs designed to selectively kill PDAC cells must remain a central research strategy. Read more

Iron Homeostasis In Bacterial Plant Colonization And Disease

Background. Iron is an essential nutrient in all orders of life. Since uptake is hampered by insolubility, plants and bacteria have evolved mechanisms for active sequestration, through the secretion of chelators called siderophores, and uptake via specific transport mechanisms. Read more

E4 DTP NERC The rise of coccolith calcification

Application procedure. Applications must be made directly to the. E4 DTP. by the deadline of 06 January 2022. Prior informal enquiries to the supervisors are welcome. Read more

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