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metabolomic PhD Projects, Programs & Scholarships

We have 20 metabolomic PhD Projects, Programs & Scholarships

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  MRC Precision Medicine DTP: Circadian biology of the systemic inflammatory response during critical illness
  Research Group: MRC Centre for Inflammation Research
  Prof D Mole, Dr T Stevenson, Prof S Reece, Dr K Prior
Application Deadline: 7 January 2019
Background. The rhythms of life are essential for maintaining health and well-being. During critical illness, circadian rhythms may be disrupted as a result of the disease process.
  MRC Precision Medicine DTP: Integrating transcriptomic and metabolomic data from people with rheumatoid arthritis to predict clinical response to drug treatment
  Research Group: Institute of Infection, Immunity & Inflammation
  Prof M Barrett, Prof I Mcinnes
Application Deadline: 7 January 2019
Supervisors. Prof Michael Barrett. Prof Iain McInnes. Dr Mick Watson. Dr Simon Rogers. PhD project summary. Modern biology has implemented technologies which enable the generation of massive datasets, dissecting the molecular composition of living things.
  Metabolomic studies of E. coli adaptation from anaerobic to aerobic growth
  Prof M P Williamson
Applications accepted all year round
Escherichia coli is a commensal organism that lives in the human gut. Occasionally it gives rise to food poisoning incidents, but mainly it is important for digestion and uptake of nutrients.
  MRC DiMeN Doctoral Training Partnership: Personalised mitochondrial health: a functional and multi-omic assessment to predict individual susceptibility to hepatotoxicity of antiepileptic drugs
  Dr A Chadwick, Dr A Alfirevic, Dr R Jenkins
Application Deadline: 21 January 2019
Background. The realisation that mitochondrial genetics are an important, and under-researched, factor in personalised medicine is growing.
  Cutting off the fuel supply to starve cancer: Identifying metabolic vulnerabilities in cancer
  Dr K Brown, Dr A. Cox
Applications accepted all year round
A universal characteristic of all cancer cells is the reprogramming of cell metabolism to provide the energy and building blocks necessary to support proliferation and survival.
  Fishing for metabolic clues: Role of the Hippo/Yap pathway in reprogramming metabolism in liver cancer
  Dr A. Cox
Applications accepted all year round
The Hippo/Yap pathway is an evolutionarily conserved cascade that plays a fundamental role in governing organ size control, stem cell homeostasis and cancer.
  Debugging Lung Disease: Applying mathematical modelling for a precision medicine approach to the Pulmonary Microbiome
  Prof K Tsaneva-Atanasova
Application Deadline: 31 January 2019
Supervisors. Professor Krasimira Tsaneva-Atanasova,College of Engineering, Mathematics and Physical Sciences, University of Exeter.
  Biomolecular taphonomy: the use of biomolecules to estimate post-mortem interval for forensic applications (RDF19/HLS/AS/PROCOPIO)
  Dr N Procopio
Application Deadline: 25 January 2019
The estimation of the time since death (or post-mortem interval, PMI) is one of the most debated topics in forensic anthropology and, despite the great number of studies conducted on this subject, it still suffers from poor precision and reliability, in particular in cases of advanced decay and/or dry remains.
  Metabolic rewiring in liver cancer: Role of oxidative stress and the Nrf2 pathway
  Dr A. Cox
Applications accepted all year round
Many of the major risks factors for developing liver cancer such as alcohol, obesity, smoking and toxin exposure share in common a role for oxidative stress.
  MRC Precision Medicine DTP: Precision medicine in Crohn’s disease and ulcerative colitis: Predicting disease flare and disease progression
  Dr C Vallejos
Application Deadline: 7 January 2019
Secondary Supervisor. Dr Charlie Lees FRCP(Ed) PhD, Consultant Gastroenterologist. This project would suit a motivated student with statistics, data science, machine learning, bioinformatics or related backgrounds.
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