"DNA sequencing technology now allows us to investigate not only the identity of organisms that are present in complex environments like soil, but also what these tiny microbes are doing.
Background – Enzyme engineering strategies, supported by computational and molecular modelling to maximise speed and efficiency, has been shown to be a powerful tool for (semi-) rational design of enzymes.1,2 We will evaluate protein mobility/dynamics, docking/binding of substrates and calculation of free energy barriers for catalysis.
The Bloomsbury Colleges PhD Studentships. 2019/20 entry. The Bloomsbury Colleges are inviting applications for 11 PhD studentships available for PhD studies beginning in the academic year 2019/20.
This project is part of the ONE Planet DTP. Find out more here. https://research.ncl.ac.uk/one-planet/. Soils in populated locations have become major sinks for the genetic potential of human-driven antibiotic resistance (AR).
Antimicrobial resistance is among the largest threats to human health, with the emergence of multidrug resistant bacterial infections meaning traditional treatment approaches are being rendered ineffective.
A number of bacterial species are able to survive in the extreme environmental conditions, e.g., hyper-arid soil of the Atacama desert (Busarakam et al., 2016; Castro et al., 2018).
The search for life in the outer solar system is centred on the search for water and the conditions which are known to support the ‘envelope of life’ on Earth.
The project will be supervised by Dr Deepak Kumaresan of Queen’s University School of Biological Sciences and by Dmitri Mauquoy of the University of Aberdeen’s School of Geosciences.
