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We have 35 metastasis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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metastasis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 35 metastasis PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis

Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more

Cancer: Characterization of EGFR signaling activated by the endothelium in the process of breast cancer metastasis to the brain

The Epidermal Growth Factor Receptor (EGFR) is important in normal physiology regulating epithelial development and homeostasis. In cancer, deregulation resulting from mutation, amplification or transcriptional upregulation promotes tumorigenesis. Read more

Cell biology and evolution of cancer metastasis

We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process. Read more

Defining the pre-metastatic niche for colorectal cancer dissemination

Colorectal cancer is a major cause of mortality and commonly associated with peritoneal metastasis. However, peritoneum, that covers visceral organs and inner cavity wall, is poorly characterised in terms of its ability to act as a metastatic niche. Read more

Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

Mechanisms of cancer cell invasion

Epithelial cancers such as breast cancer become difficult to treat when they invade the surrounding tissues, eventually entering the blood stream and spreading to other parts of the body to form metastases. Read more

Investigating the clinical and molecular significance of the microbiome in breast cancer

Breast Cancer (BC) is the most common cancer in the UK, accounting for 15% of new cancer cases. There is a significant unmet clinical need to understand why some cancers do not respond to treatment and what drives metastasis. Read more

The role of calcium signalling in regulating of tumour cell behaviour

Metastasis is the major cause of mortality in human cancers, yet we know relatively little of the fundamental biology that underlies the important transition to invasive malignancy. Read more

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