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metastasis PhD Projects, Programmes & Scholarships
We have 39 metastasis PhD Projects, Programmes & Scholarships
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4-year PhD Studentship: Development of a cheap sensitive blood test for early detection of brain metastasis using fluorescent carbon dots and nanophotonics
Development of a cheap sensitive blood test for early detection of brain metastasis using fluorescent carbon dots and nanophotonics. Read more
Characterization of the molecular mechanisms of breast cancer metastasis to bone: from basic research to biomarkers
About the Project. Breast cancer is responsible for over 300,000 cancer diagnoses within the UK per annum, and it is estimated that one in 7 women will develop breast cancer. Read more
Epi-Genomic and Epi-Transcriptomic Aberrations in Breast Cancer Brain Metastasis
A SFI funded PhD position is available within the Department of Surgery, Royal College of Surgeons, Dublin, Ireland for a highly motivated person with an upper second or first class honours degree or Masters degree in clinical biology or a related subject. Read more
Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis
Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more
Cell biology and evolution of cancer metastasis
We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process. Read more
The stiffness of extracellular fibres and metastasis
This role supports an active research program to assess the molecular mechanisms underlying adhesive, mechanical and motile defects of metastasising cells. Read more
The role of dynamic changes in proteome in pancreatic cancer initiation
Introduction. Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate under 7%. Better understanding of PDAC formation will help improve this. Read more
Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer
Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more
Prostate cancer signalling to the bone micro-environment - from molecular characterization to potential novel therapies.
About the Project. Prostate cancer is responsible for over 52,000 cancer diagnoses within the UK per annum, and is the most common cancer in males, accounting for 27% of all new cancer cases diagnosed within men in 2016-2017. Read more
Dissecting the role of Activin signalling in Pancreatic Ductal Adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is currently the fourth leading cause of cancer associated mortality with <7% patients surviving for 5 years following diagnosis. Read more
Preclinical investigation of novel super-selective mTOR inhibitors in colorectal cancer
The development of potent and selective small molecules that mediate dose-dependent inhibition of a protein in its natural environment is essential to elucidate the role of such nominated target in normal and pathological settings [1]. Read more
Developing new cancer therapeutic agents from foodstuff: characterizing galectin interaction with novel inhibitors
Applications will be reviewed until a suitable candidate is appointed. Galectins are a family of carbohydrate-binding proteins that are commonly over-expressed by many types of cancers such as colorectal, lung, breast, prostate cancer and melanoma. Read more
Developing novel treatments for refractory and relapsed osteosarcoma using advanced pre-clinical models
Osteosarcoma is the most common bone cancer in children. Patients presenting without metastasis have a 5-year survival rate of 65%. Read more
Determining the roles that GRK and arrestin proteins play in the development of hypertension and vascular disease
G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more
Breast Cancer Omics and Modelling
Background and goals. Breast cancer is the major cause of death among women and 90% of deaths are caused by incurable metastasis. Read more