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metastasis PhD Projects, Programmes & Scholarships

We have 39 metastasis PhD Projects, Programmes & Scholarships

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We have 39 metastasis PhD Projects, Programmes & Scholarships

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Epi-Genomic and Epi-Transcriptomic Aberrations in Breast Cancer Brain Metastasis

A SFI funded PhD position is available within the Department of Surgery, Royal College of Surgeons, Dublin, Ireland for a highly motivated person with an upper second or first class honours degree or Masters degree in clinical biology or a related subject. Read more

Assessing the molecular mechanisms by which Cathepsin V promotes breast cancer growth and metastasis

Targeted therapies such as tamoxifen, fulvestrant and anastrozole have exhibited significant clinical success since being introduced as treatments for Estrogen Receptor positive (ER+) breast cancer patients. Read more

Cell biology and evolution of cancer metastasis

We are interested in the spread of cancer, a process called metastasis. Metastasis is responsible for the majority of cancer deaths and there are currently no effective treatments to stop this process. Read more

Mechanisms of Cancer Stem Cell Survival, Metastasis Formation and Immune Evasion in Cancer

Recent research suggests that cancer cells within a tumour represent a highly heterogeneous cell population. In particular many tumours contain small percentage of cells that share several characteristics with stem cells. Read more

Prostate cancer signalling to the bone micro-environment - from molecular characterization to potential novel therapies.

About the Project. Prostate cancer is responsible for over 52,000 cancer diagnoses within the UK per annum, and is the most common cancer in males, accounting for 27% of all new cancer cases diagnosed within men in 2016-2017. Read more

Preclinical investigation of novel super-selective mTOR inhibitors in colorectal cancer

The development of potent and selective small molecules that mediate dose-dependent inhibition of a protein in its natural environment is essential to elucidate the role of such nominated target in normal and pathological settings [1]. Read more

Developing new cancer therapeutic agents from foodstuff: characterizing galectin interaction with novel inhibitors

Applications will be reviewed until a suitable candidate is appointed. Galectins are a family of carbohydrate-binding proteins that are commonly over-expressed by many types of cancers such as colorectal, lung, breast, prostate cancer and melanoma. Read more

Determining the roles that GRK and arrestin proteins play in the development of hypertension and vascular disease

G protein-coupled receptors (GPCRs) constitute a very large family of heptahelical, integral membrane proteins that mediate a wide variety of physiological processes ranging from the transmission of light and odorant signals to the mediation of neurotransmission and hormonal actions. Read more

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