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methylation PhD Projects, Programs & Scholarships

We have 32 methylation PhD Projects, Programs & Scholarships

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  Signalling to the Code: Understanding the biochemical regulation of DNA methylation in stem cells
  Dr M Christophorou
Application Deadline: 3 December 2019

Funding Type

PhD Type

How do our cells, all of which have exactly the same set of genes, adopt such different fates, morphologies and functions? How do cells then respond to…
  Establishment of germline-specific DNA methylation in plants (FENGJ20DTP)
  Dr X Feng
Application Deadline: 25 November 2019

Funding Type

PhD Type

Our recent work demonstrated distinctive DNA methylation occurs at hundreds of genes across the entire male germline in plants. This germline-specific methylation is catalysed by a ubiquitous methylation pathway, and regulates meiosis by controlling gene expression and splicing.
  The role of DNA methylation on neuronal activity in health and disease
  Dr D Goffin, Prof M Whittington
Application Deadline: 30 June 2020

Funding Type

PhD Type

Despite identical genetic sequences, neurones are highly divergent with distinct locations, morphology, connectivity, electrophysiology and transcriptional profiles.
  Applying machine learning and artificial intelligence to decode complex patterns of DNA methylation (HALLE20DTP1)
  Prof A Hall
Application Deadline: 25 November 2019

Funding Type

PhD Type

In plants DNA methylation plays an important role in regulating gene expression. DNA methylation can also act as a “soft mutation” creating phenotypic variation.
  Understanding genome regulation via DNA methylation and enhancer interactions in cancer
  Dr M Parry, Dr A Chatterjee
Applications accepted all year round

Funding Type

PhD Type

Gene expression changes are likely in cancer patients, as well as methylation changes. However, there is a paucity of enhancer data for cancer patients.
  Identifying causal pathways to disease using DNA methylation derived scores.
  Dr J Min
Application Deadline: 25 November 2019

Funding Type

PhD Type

The University of Bristol is offering a 3.5 year full time PhD in research around Population Health to start in 2020. This studentship is funded through GW4 BioMed MRC Doctoral Training Partnership.
  RNA Methylation in normal and malignant blood development
  Dr L. Kats
Applications accepted all year round

Funding Type

PhD Type

As is the case with DNA and histones, RNA can also be modified and indeed more than 100 chemical groups that decorate all four canonical RNA nucleotides have been described.
  Ligand-induced selective signalling of peptide GPCRs and their potential role in the regulation of mRNA methylation
  Prof Z Lu, Dr J Meng, Dr R Rong
Applications accepted all year round

Funding Type

PhD Type

G protein-coupled receptors (GPCRs) modulate the majority of physiological and pathological processes and constitute the largest family of cell surface receptors and drug targets.
  The epigenetics of Parkinson’s disease: searching for novel drug targets. PhD in Medical Studies (MRC GW4 BioMed DTP)
  Dr A Migdalska-Richards
Application Deadline: 25 November 2019

Funding Type

PhD Type

Supervisory team. Dr Anna Migdalska-Richards, Institute of Clinical Biosciences, College of Medicine and Health, University of Exeter.
  Expanding the utility of DNA methylation profiles in peripheral tissues using captured biological variation
  Dr M Suderman
Application Deadline: 25 November 2019

Funding Type

PhD Type

Medicine has benefited from the use of molecular biomarkers for estimating health risks, diagnosing disease, selecting treatments and predicting treatment response.
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