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methylation PhD Projects, Programs & Scholarships

We have 24 methylation PhD Projects, Programs & Scholarships

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  Understanding transcription mediated methylation of intragenic CpG islands in health and disease
  Dr C Tufarelli, Prof S Cowley
Application Deadline: 5 May 2019
1. Project outline describing the scientific rationale of the project (max 4,000 characters incl. spaces and returns). DNA methylation is an epigenetic modification that affects gene expression without altering gene sequences.
  4 Year Wellcome Trust PhD Programme: Dissecting the epigenetic regulation of enhancer function in hematopoiesis
  Dr K Rasmussen
Application Deadline: 8 April 2019
The epigenetic mark of DNA methylation is established by DNMT (DNA methyltransferase) enzymes and has been shown to correlate with transcriptional states and influence cell identity and tumorigenesis in mammalian cells.
  MRC DTP 4 Year PhD Programme: Dissecting the epigenetic regulation of enhancer function in hematopoiesis
  Dr K Rasmussen, Dr G Schweikert
Application Deadline: 19 April 2019
This project is part of our exciting and challenging University of Dundee 4-year MRC DTP Programme in Quantitative and Interdisciplinary approaches to biomedical science.
  The Epigenetics of Child Language - exploring the involvement of DNA methylation in the development of languageskills in children.
  Dr G Sharp
Applications accepted all year round
Oral Language skills are essential to everyday life. Most children acquire them effortlessly but. some are “language impaired”. It is currently unclear what causes this variability between.
  Modelling the interface of metabolism, methylation and mitochondria in prostate cancer
  Prof A Lynch
Applications accepted all year round
The interface of metabolism, methylation and mitochondria is of key importance for understanding the aetiology, biology and prognosis of prostate cancer[1].
  Investigating the role of lysine methylation in the DNA damage response.
  Dr M Higgs
Applications accepted all year round
Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including haematopoietic abnormalities and developmental disorders as well as cancer.
  Epigenetics of neonicotinoids in an important insect pollinator
  Dr E Mallon, Dr E Rosato
Application Deadline: 5 May 2019
This project will contribute to assessing an important threat to food crop pollination by quantifying, for the first time, the epigenetic effects of neonicotinoids on bumblebees.
  Metabolic programming: Role of micronutrient (B12) deficiency and associated epigenetic marks
  Dr A Antonysunil
Applications accepted all year round
The global epidemic of childhood obesity is a major public health issue. Although current adverse lifestyle (nutrition and physical inactivity) contributes to obesity, a growing body of evidence links early life nutritional adversity to the development of obesity and metabolic disorders in children.
  Epitranscriptomic mechanisms in the maternal to zygotic transition of vertebrate embryos
  Dr M Soller, Prof F Mueller
Applications accepted all year round
Most mRNAs contain modified nucleotides in mRNA, but we know very little about their function (Haussmann et al, 2016, Dezi et al, 2016, Roignant and Soller, 2017).
  Using synthetic biology to understand how the epigenome is programmed in cancer
  Research Group: MRC Human Genetics Unit
  Dr D Sproul:
Application Deadline: 19 April 2019
This is one of several projects available on an MRC funded 4-year multi-disciplinary PhD programme in Human Genetics, Genomics and Disease at the MRC Human Genetics Unit (HGU), part of the Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh.
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