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methylation PhD Projects, Programs & Scholarships

We have 37 methylation PhD Projects, Programs & Scholarships

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  Understanding transcription mediated methylation of intragenic CpG islands in health and disease
  Dr C Tufarelli, Prof S Cowley
Application Deadline: 6 January 2019
1. Project outline describing the scientific rationale of the project (max 4,000 characters incl. spaces and returns). DNA methylation is an epigenetic modification that affects gene expression without altering gene sequences.
  MRC Precision Medicine DTP: Investigating the mechanisms underlying disease using multiOmics data
  Research Group: MRC Human Genetics Unit
  Dr P Navarro, Dr S Knott, Dr C Amador, Mr K Rawlik
Application Deadline: 7 January 2019
Background. Advances in genotyping technologies and computational capacities have brought new insights into the genetic mechanisms influencing disease.
  Dissecting the role of DNA methylation in spiral cleavage
  Dr JM Martin, Dr R Lowe
Application Deadline: 31 January 2019
Nearly all animals originate during a process called embryogenesis, in which a single cell – the zygote – develops into a multicellular complex organism.
  4 Year Wellcome Trust PhD Programme: Dissecting the epigenetic regulation of enhancer function in hematopoiesis
  Dr K Rasmussen
Application Deadline: 14 December 2018
The epigenetic mark of DNA methylation is established by DNMT (DNA methyltransferase) enzymes and has been shown to correlate with transcriptional states and influence cell identity and tumorigenesis in mammalian cells.
  MRC DTP 4 Year PhD Programme: Dissecting the epigenetic regulation of enhancer function in hematopoiesis
  Dr K Rasmussen, Dr G Schweikert
Application Deadline: 18 January 2019
This project is part of our exciting and challenging University of Dundee 4-year MRC DTP Programme in Quantitative and Interdisciplinary approaches to biomedical science.
  The Epigenetics of Child Language - exploring the involvement of DNA methylation in the development of languageskills in children.
  Dr G Sharp
Applications accepted all year round
Oral Language skills are essential to everyday life. Most children acquire them effortlessly but. some are “language impaired”. It is currently unclear what causes this variability between.
  Modelling the interface of metabolism, methylation and mitochondria in prostate cancer
  Prof A Lynch
Applications accepted all year round
The interface of metabolism, methylation and mitochondria is of key importance for understanding the aetiology, biology and prognosis of prostate cancer[1].
  MRC Precision Medicine DTP: Using machine learning to dissect genetic effects on DNA methylation heterogeneity in cancer
  Research Group: MRC Human Genetics Unit
  Dr D Sproul:, Dr G Sanguinetti
Application Deadline: 7 January 2019
Background. Genetic and epigenetic heterogeneity are fundamental hallmarks of cancer. Advances in high-throughput sequencing have resulted in the extensive characterisation of intra-tumoural genetic heterogeneity.
  Genomics of Inflammation and Cancer Immunology: inter-individual variation in response to checkpoint inhibitor therapy
  Dr B Fairfax
Application Deadline: 11 January 2019
We work on characterising inter-individual variation in human immune responses. Checkpoint inhibitor immunotherapy has revolutionised the management of multiple cancers, yet our understanding of how the response to these treatments diverges between patients is limited.
  Investigating the role of lysine methylation in the DNA damage response.
  Dr M Higgs
Applications accepted all year round
Our genomic DNA is under constant attack from DNA damaging agents, which are a continuing threat to genomic integrity. Defective resolution of DNA damage underlies several human diseases, including haematopoietic abnormalities and developmental disorders as well as cancer.
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