Aggression in group housed male mice is a major concern from both an animal welfare and scientific perspective. Surprising little is known about the social behaviour of male mice in the laboratory environment and therefore what factors trigger aggression or beneficial husbandry methods. Read more
Cardiovascular disease is the leading cause of premature death in chronic kidney disease [1] and proteinuria is an independent risk factor of cardiovascular mortality [2]. Read more
Using a combination of patient samples and mouse models, we study the causes and developmental origins of skull malformation. The work ranges from screening human DNA for new mutations, to use of genome editing and single cell transcriptomics to model the developmental causes of these malformations in mice. Read more
This project is available through the MIBTP programme. The successful applicant will join the MIBTP cohort and will take part in all of the training offered by the programme. Read more
In the developing world, parasitic helminths infect a large proportion of the population – up to 1 billion people are infected with soil-transmitted helminth (STH) infections worldwide. Read more
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
The focus of the Nerlov laboratory is combining single cell biology (single cell RNAseq, ATACseq and functional analysis) with advanced mouse genetics to study hematopoietic stem– and progenitor cells in normal development and during ageing. Read more
Ageing is a biological process that affects all humans. Despite the scientific advances of the past decades, the mechanisms that lead to ageing are not fully understood. Read more
We study how the heart meets its high and variable energy demands in order to identify novel strategies that may be therapeutically beneficial in disease. Read more
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