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microglia PhD Projects, Programs & Scholarships

We have 9 microglia PhD Projects, Programs & Scholarships

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  Exploring Parkinson’s related gene function in hiPS-macrophages and microglia
  Prof W S James, Dr S Cowley
Application Deadline: 10 January 2020

Funding Type

PhD Type

The macrophage is an evolutionarily ancient sentinel of the health of all of the body’s tissues. clearing away dead cells and debris; as brain-resident microglia, remodelling defunct neuronal connections; nurturing tissue stem cells; detecting and responding to pathogens.
  Anti-inflammatory actions of metabolites on macrophages and microglia
  Prof D R Greaves
Application Deadline: 10 January 2020

Funding Type

PhD Type

Background. It is clear that inflammation underlies many important chronic disease states in both the central nervous system (CNS) e.g.
  Identifying the role of glycosaminoglycans and microglia in early pathology of mucopolysaccharide diseases
  Dr B BIgger, Dr R Holley, Prof S Flitsch
Applications accepted all year round

Funding Type

PhD Type

Mucopolysaccharidoses (MPS) are inherited metabolic disorders caused by the deficiency of specific lysosomal enzymes required for the catabolism of glycosaminoglycans (GAGs) where each MPS type lacks a specific enzyme resulting in the build-up of GAGs in all cells of the body.
  Tackling neurovascular dysfunction in dementia: a cell biology and biomaterials approach
  Prof N Hooper, Dr M Domingos, Dr T Wang
Applications accepted all year round

Funding Type

PhD Type

Neurovascular dysfunction is a central process in the pathogenesis of Alzheimer’s disease and other dementias. In the brain, vascular and neuronal structures are tightly integrated forming the multicellular neurovascular unit comprising endothelial cells, pericytes, astrocytes, microglia and neurons.
  Investigating how activated monocytes/macrophages infiltrate into the brain to stimulate neuroimmune responses
  Dr R Chang
Applications accepted all year round

Funding Type

PhD Type

The Laboratory of Neurodegenerative Disease (Dr. Raymond CC Chang’s Lab. Facebook. https://www.facebook.com/Neurodeglab) is looking for a pro-active PhD student with first class honor or equivalent.
  (MRC DTP) Understanding the regulation of an IL-1alpha inflammatory reaction
  Dr D Brough, Prof S Allan, Dr J Rivers-Auty
Application Deadline: 15 November 2019

Funding Type

PhD Type

Background. Inflammation is a response of the innate immune system that controls infection and promotes resistance and tissue repair.
  Investigating the link between amyloid-β oligomers, neuroinflammation and cognitive deficits in preclinical models for Alzheimer’s Disease
  Dr M Harte, Prof J Neill
Applications accepted all year round

Funding Type

PhD Type

Currently four out of the five pharmacological treatments used for Alzheimer’s disease (AD) are acetylcholinesterase inhibitors aimed at boosting the amount of acetylcholine in the brain, with the fifth being an N-methyl-D-aspartate (NMDA) receptor antagonist.
  Understanding how inflammation affects brain disease
  Dr D Brough, Dr C Lawrence
Applications accepted all year round

Funding Type

PhD Type

We know that both peripheral and central inflammation influence neurological disease. This influence progresses and worsens diverse brain diseases, but the mechanisms involved are poorly understood.
  Targeting inflammation to prevent brain swelling following paediatric head injury
  Dr F Corrigan
Applications accepted all year round

Funding Type

PhD Type

Applications are invited to undertake a PhD/Higher Degree by Research (HDR) to investigate how the inflammatory response to a traumatic brain injury differs in the paediatric population compared to adults.
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