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microglia PhD Projects, Programmes & Scholarships
We have 10 microglia PhD Projects, Programmes & Scholarships
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Targeting protein acetylation to reduce microglia activation in neurodegenerative disorders
Recently, inhibitors of histone deacetylase enzymes (HDACs) have been identified as having potential therapeutic value for a range of neuronal disorders including Alzheimer’s disease, dementia and stroke [1, 2]. Read more
4-year PhD Studentship: Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Alzheimer’s disease (AD) is a devastating progressive neurological disease, and a major increasing global health challenge. Read more
Early life perturbations and neurological disorders in later life
The formation of the brain involves a complex choreography of events and players during development. While this process is continuous, there are however critical periods in which this process is particularly susceptible to perturbations. Read more
The Role of Microglia & Astrocytes in Neurodegeneration & Neuroprotection following Traumatic Brain Injury
Imperial College London
Department of Surgery & Cancer, Anaesthetics Pain Medicine & Intensive Care Section
The Neurotrauma & Neuroprotection Laboratory uses a variety of in vivo and in vitro techniques to understand the pathophysiology of traumatic brain injury and to evaluate the efficacy of novel treatments for TBI such as noble gases. Read more
Neuroimmunology of concussion
Concussion, or mild traumatic brain injury, affects millions world-wide each year. It is now appreciated that a history of concussion increases the risk of developing long-term emotional and neurocognitive disorders. Read more
Apolipoprotein E-targeted stem cell gene therapy for people with Alzheimer’s disease
Perros Trust-supported 1 Year Full MSc R Scholarship for students of Black or Mixed Black Heritage backgrounds. Project Description. Read more
Investigating the link between amyloid-β oligomers, neuroinflammation and cognitive deficits in preclinical models for Alzheimer’s Disease
Currently four out of the five pharmacological treatments used for Alzheimer’s disease (AD) are acetylcholinesterase inhibitors aimed at boosting the amount of acetylcholine in the brain, with the fifth being an N-methyl-D-aspartate (NMDA) receptor antagonist. Read more
The role of neural stem cells and new neurons in regulating energy homeostasis
The project combines molecular biology and neuroscience to investigate the role of neural stem cells and new neurons in regulation of body weight. Read more
Understanding how inflammation affects brain disease
We know that both peripheral and central inflammation influence neurological disease. This influence progresses and worsens diverse brain diseases, but the mechanisms involved are poorly understood. Read more
Molecular mechanism of innate immunity mediated by the Toll/IL1 receptor signalling pathways
Our research aims to elucidate the molecular and cellular regulation of innate immune signal transduction in the context of infectious, inflammatory and autoimmune disease. Read more
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