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We have 11 microglia PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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microglia PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

We have 11 microglia PhD Projects, Programmes & Scholarships PhD Projects, Programmes & Scholarships

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Computational and cell biological studies to understand the regulation of microglia by a novel Alzheimer’s disease risk gene

Advances have been made through large-scale study of patients genetic make-up, which have pointed to a number of genes, particularly those of the immune system, being involved in the development of Alzheimer’s disease. Read more

Early life perturbations and neurological disorders in later life

The formation of the brain involves a complex choreography of events and players during development. While this process is continuous, there are however critical periods in which this process is particularly susceptible to perturbations. Read more
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Lipid droplets and the regulation of inflammation by macrophages

Lipid droplets are important intracellular particles that comprise neutral lipids surrounded by a phospholipid monolayer. They are a major reservoir for lipids that are then provided for energy, membrane biosynthesis and for signalling intermediates. Read more

Neuroimmunology of concussion

Concussion, or mild traumatic brain injury, affects millions world-wide each year. It is now appreciated that a history of concussion increases the risk of developing long-term emotional and neurocognitive disorders. Read more

MScR - Early-life stress, susceptibility to mental health disorders and glia: central immune response in a rat model of pre-term birth

Depression and anxiety are the most prevalent mental health disorders affecting 1 in 4 people in the UK. Depression is the second most common cause of disability and together with other mental health disorders costs the UK economy an estimated £105 billion per year. Read more

Investigating the link between amyloid-β oligomers, neuroinflammation and cognitive deficits in preclinical models for Alzheimer’s Disease

Currently four out of the five pharmacological treatments used for Alzheimer’s disease (AD) are acetylcholinesterase inhibitors aimed at boosting the amount of acetylcholine in the brain, with the fifth being an N-methyl-D-aspartate (NMDA) receptor antagonist. Read more

Understanding how inflammation affects brain disease

We know that both peripheral and central inflammation influence neurological disease. This influence progresses and worsens diverse brain diseases, but the mechanisms involved are poorly understood. Read more
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