TREM2 regulation of microglial dynamics
Prof J Kittler
Application Deadline:
8 April 2019
This studentship is focused on understanding the cellular basis of microglial function through the study of TREM2, with the aim of opening up new avenues for intervention in disease.
Using biomaterials and 3D bioprinting to model the neurovascular unit in dementia
Prof N Hooper, Dr M Domingos, Dr T Wang
Applications accepted all year round
Neurovascular dysfunction is a central process in the pathogenesis of Alzheimer’s disease and other dementias. In the brain, cerebrovasculature and neuronal structures are tightly integrated forming the multicellular neurovascular unit comprising endothelial cells, astrocytes, microglia and neurons.
Understanding how inflammation affects brain disease
Dr D Brough, Dr C Lawrence
Applications accepted all year round
We know that both peripheral and central inflammation influence neurological disease. This influence progresses and worsens diverse brain diseases, but the mechanisms involved are poorly understood.
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