The recently founded Biomedical Sciences doctoral degree programme has been created through the merging of the following originally individual study disciplines. Read more
Job description. The fellowship is for a period of 3 years. Starting date. as soon as possible. No one can be appointed for more than one fixed-term at the same institution. Read more
Job description. The fellowship is for a period of 3 years. Starting date. as soon as possible. No one can be appointed for more than one fixed-term at the same institution. Read more
Protein interactions underlie most biological processes but are challenging to target using small molecule drugs. Many protein interactions are mediated by short-linear-interacting motifs (SLiMs) that range from 3-12 amino acid residues (1, 2). Read more
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
Blood cell differentiation is one of the best characterised models to study how normal tissue-specific stem cells give rise to diverse cell types. Read more
Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more
Genomic instability (GI) is a hallmark of cancer that plays a central role in its initiation and development. GI can arise as a result of germline and somatic mutations that compromise a cell’s ability to accurately sense, signal or repair DNA damage. Read more
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more
De novo mutations (DNMs) are a significant contributor to human disease, affecting ~1:300 new births. We study the mechanisms by which these spontaneous mutations arise in the first instance, concentrating on the tissue where most originate, the human testis. Read more
Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more
Our laboratory is interested in the general question of how mammalian genes are switched on and off during lineage commitment and differentiation. Read more
Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more
Our work has shown that metabolism both generalized and intrinsic to blood stem cells unleashes reactive metabolites such as the aldehydes – formaldehyde and acetaldehyde. Read more
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